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Monosensitization and polysensitization in allergic rhinitis

2011; Elsevier BV; Volume: 22; Issue: 6 Linguagem: Inglês

10.1016/j.ejim.2011.05.009

1879-0828

Giorgio Ciprandi, Ignazio Cirillo,

Nasal Surgery and Airway Studies

Abstract Background Polysensitization is common in patients with allergic rhinitis (AR) and may affect clinical feature. However, there are patients who remain monosensitized. Objective This cross-sectional study aimed at evaluating a large cohort of AR patients to define the percentage and the features of mono- and poly-sensitized subjects. Methods This observational cross-sectional study included a large group of AR patients: 2415 subjects (1958 males, mean age 24.6±5years) were consecutively evaluated. Symptom severity, type and number of sensitizations, and AR duration were considered. Results 621 patients (25.7%) were monosensitized: 377 to Parietaria , 194 to house dust mites, 19 to birch, 17 to grasses, 12 to molds, 2 to olive, and 1 to cypress. There was no difference between mono- and polysensitized patients concerning the duration of rhinitis (6±2.14years vs 6±3.7). Severity of symptoms was higher in polysensitized patients than in monosensitized (p<0.05); in addition, there was a difference among monosensitized patients: Parietaria -allergy induces the most severe symptoms. Conclusion This study conducted in a large AR population might suggest that monosensitized and polysensitized AR patients could constitute two different categories. In addition, the specific type of allergy may condition the clinical feature.