Artigo Acesso aberto Revisado por pares

The Effect of "Sympatholytic Drugs on the Cardiovascular Responses to Epinephrine and Norepinephrine in Man

1951; Lippincott Williams & Wilkins; Volume: 3; Issue: 2 Linguagem: Inglês

10.1161/01.cir.3.2.254

ISSN

1524-4539

Autores

Edward D. Freis, J. CALVIN MACKAY, W. F. Oliver,

Tópico(s)

Chemical synthesis and alkaloids

Resumo

Under controlled conditions the effects of various "sympatholytic" agents on the cardiovascular responses to epinephrine and norepinephrine were compared in man. The dosages of the sympatholytic drugs administered approximated those usually employed clinically. Such basic data are given for the following agents: Dibenamine, the imidazoline derivatives [Priscoline and Regitine (C-7337)], the dihydrogenated alkaloids of ergot (D.H.K. and C.C.K.), L-hydrazinophthalazine (C-5968), tetraethylammonium, and hexamethonium (C6).

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