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Neuromodulation of Decision-Making in the Addictive Brain

2010; Taylor & Francis; Volume: 45; Issue: 11 Linguagem: Inglês

10.3109/10826084.2010.482434

1532-2491

Shirley Fecteau, Felipe Fregni, Paulo S. Boggio, Joan A. Camprodon, Álvaro Pascual‐Leone,

Mind wandering and attention

Noninvasive brain stimulation of the dorsolateral prefrontal cortex with repetitive transcranial magnetic stimulation and transcranial direct current stimulation can modify decision-making behaviors in healthy subjects. The same type of noninvasive brain stimulation can suppress drug craving in substance user patients, who often display impaired decision-making behaviors. We discuss the implications of these studies for the cognitive neurosciences and their translational applications to the treatment of addictions. We propose a neurocognitive model that can account for our findings and suggests a promising therapeutic role of brain stimulation in the treatment of substance abuse and addictive behavior disorders.