Dose-dependent effects of hydrocortisone on memory in human males
1986; Elsevier BV; Volume: 36; Issue: 2 Linguagem: Inglês
10.1016/0031-9384(86)90017-x
ISSN1873-507X
AutoresBill E. Beckwith, Thomas V. Petros, Cris Scaglione, J. Craig Nelson,
Tópico(s)Hormonal Regulation and Hypertension
ResumoEighty male undergraduates were administered either glucose or 5, 10, 20, or 40 mg of hydrocortisone in a double-blind procedure. After 60 min they were asked to listen to eight 12 word lists and then asked to recall the words. In addition to the expected effects of rate of presentation, serial position, and practice there was a significant interaction between dose of hydrocortisone and practice. Early recall was facilitated by all doses used whereas later recall was facilitated by treatment with 40 mg and impaired by treatment with 5 mg. These findings are discussed in the context of the effects of pituitary adrenocortical hormones and memory function.
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