Selective ring-opening reaction of styrene oxide with lithium azide in the presence of cyclodextrins in aqueous media
1992; Elsevier BV; Volume: 3; Issue: 2 Linguagem: Inglês
10.1016/s0957-4166(00)80202-5
ISSN1362-511X
AutoresAlain Guy, Joël Doussot, Robert Garreau, A. GODEFROY‐FALGUIERES,
Tópico(s)Chemical Synthesis and Analysis
ResumoRegioselective ring-opening of racemic styrene oxide was achieved by lithium azide in the presence of β-cyclodextrin in aqueous media. Kinetic resolution of racemic epoxide was observed and 1-phenyl-2-azido-ethanol was obtained with 78 % ee.
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