Portal de Periódicos da CAPES

Longitudinal melanonychia associated with hydroxyurea therapy in a patient with essential thrombocytosis

1999; Wiley; Volume: 13; Issue: 2 Linguagem: Inglês

10.1111/j.1468-3083.1999.tb00868.x

1468-3083

Arnon D. Cohen, Dafnah Hallel‐Halevy, L Hatskelzon, Eyal Peretz, Sima Halevy,

Infectious Diseases and Mycology

Occurrence of skin lesions during long-term therapy with hydroxyurea are well described, but there have been only a few case reports of longitudinal melanonychia associated with hydroxyurea treatment. We report herein longitudinal melanonychia associated with hydroxyurea therapy in a subject with essential thrombocytosis. The prolonged time lapse (1 year) between initiation of hydroxyurea therapy and the onset of the longitudinal melanonychia should be noted.