Pt-Catalyzed Pentannulations from In Situ Generated Metallo−Carbenoids Utilizing Propargylic Esters
2005; American Chemical Society; Volume: 127; Issue: 36 Linguagem: Inglês
10.1021/ja053192c
ISSN1943-2984
AutoresB. A. Bhanu Prasad, Francis K. Yoshimoto, Richmond Sarpong,
Tópico(s)Synthetic Organic Chemistry Methods
ResumoA highly selective and efficient Pt-catalyzed pentannulation reaction beginning from propargylic esters is described. The key to this reaction is the use of a PtCl2(PPh3)2/PhIO catalyst combination that allows the in situ generation of Pt−carbenoid intermediates, which lead to good yields (61−84%) of the desired pentannulated compounds.
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