Revisão Acesso aberto Revisado por pares

Ricin Poisoning

2005; American Medical Association; Volume: 294; Issue: 18 Linguagem: Inglês

10.1001/jama.294.18.2342

ISSN

1538-3598

Autores

Jennifer Audi, Martin Belson, Manish M. Patel, Joshua G. Schier, John Osterloh,

Tópico(s)

Plant tissue culture and regeneration

Resumo

concern about ricin, a potent biologic toxin, as a possible terrorist weapon has necessitated a comprehensive review of this poison. 1The Centers for Disease Control and Prevention (CDC) categorizes ricin as a Category B agent (second-highest priority), as it is moderately easy to disseminate, resulting in low mortality but moderate to high morbidity, and requires specific enhancement of the CDC's diagnostic and disease surveillance capacity. 2 Such agents are not routinely encountered, so heightened awareness in the health care community and a strong public health infrastructure are necessary for detection and response.We therefore have summarized the literature on ricin poisoning and provided recommendations for clinicians and public health professionals dealing with a ricin attack against a civilian population. EVIDENCE ACQUISITIONUsing PubMed, we searched MEDLINE and OLDMEDLINE databases from January 1950 to August 2005 using the keywords ricin, ricinus communis, ricinine, plant toxins, castor beans, castor dust, and castor oil.Keywords were used alone and with the modifiers toxicity, poisoning

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