Portal de Periódicos da CAPES

Interference between Streptococcus pneumoniae and Staphylococcus aureus : In Vitro Hydrogen Peroxide-Mediated Killing by Streptococcus pneumoniae

2006; American Society for Microbiology; Volume: 188; Issue: 13 Linguagem: Inglês

10.1128/jb.00317-06

1098-5530

Gili Regev‐Yochay, Krzysztof Trzciński, Claudette M. Thompson, Richard Malley, Marc Lipsitch,

Streptococcal Infections and Treatments

The bactericidal activity of Streptococcus pneumoniae toward Staphylococcus aureus is mediated by hydrogen peroxide. Catalase eliminated this activity. Pneumococci grown anaerobically or genetically lacking pyruvate oxidase (SpxB) were not bactericidal, nor were nonpneumococcal streptococci. These results provide a possible mechanistic explanation for the interspecies interference observed in epidemiologic studies.