Molecular Biology of Myelin Proteins from the Central Nervous System
1988; Wiley; Volume: 51; Issue: 1 Linguagem: Inglês
10.1111/j.1471-4159.1988.tb04827.x
ISSN1471-4159
Autores Tópico(s)Neurological diseases and metabolism
ResumoJournal of NeurochemistryVolume 51, Issue 1 p. 1-14 Molecular Biology of Myelin Proteins from the Central Nervous System Anthony T. Campagnoni, Corresponding Author Anthony T. Campagnoni Mental Retardation Research Center and Brain Research Institute, UCLA School of Medicine, Los Angeles, California, U.S.A.Address correspondence and reprint requests to Dr. A. T. Campagnoni at Mental Retardation Research Center and Brain Research Institute, UCLA School of Medicine, 760 Westwood Plaza, Los Angeles, CA 90024, U.S.A.Search for more papers by this author Anthony T. Campagnoni, Corresponding Author Anthony T. Campagnoni Mental Retardation Research Center and Brain Research Institute, UCLA School of Medicine, Los Angeles, California, U.S.A.Address correspondence and reprint requests to Dr. A. T. Campagnoni at Mental Retardation Research Center and Brain Research Institute, UCLA School of Medicine, 760 Westwood Plaza, Los Angeles, CA 90024, U.S.A.Search for more papers by this author First published: July 1988 https://doi.org/10.1111/j.1471-4159.1988.tb04827.xCitations: 190Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Adams D. H. and Osborne J. (1973) A developmental study of the relationship between the protein components of rat CNS my-elin. Neurobiology 3, 91–112. Agrawal H. C. and Hartman B. K. (1980) Proteolipid protein and other proteins of myelin, in Proteins of the Nervous System, 2nd ed. ( D. M. Schneider, eds), pp. 145–169. Raven Press, New York . Agrawal H. C., Agrawal D., and Jenkins R. P. (1986) Immuno-chemical evidence for phosphorylation of a new 23 K basic protein in rat brain myelin. Neurochem. Res. 11, 375–382. Amur S. G., Shanker G., Cochran J. M., Ved H. S., and Pieringer R. A. (1986) Correlation between inhibition of myelin basic protein (arginine) methyltransferase by sinefungin and lack of compact myelin formation in cultures of cerebral cells from embryonic mice. J. Neurosci. Res. 16, 367–376. Arquint M., Roder J., Chia L.-S., Down J., Wilkinson D., Bayley H., Braun P., and Dunn R. (1987) Molecular cloning and primary structure of myelin-associated glycoprotein. Proc. Natl. Acad. Sci. USA 84, 600–604. Bansal G., Martenson R. E., Leveille P., and Campagnoni A. T. (1987) Characterization of a novel monoclonal anti-myelin basic protein antibody: use in immunoblotting and immuno-histochemical studies. J. Neuroimmunol. 15, 279–294. Barbarese E., Carson J. H., and Braun P. E. (1978) Accumulation of the four myelin basic proteins in mouse brain during development. J. Neurochem. 31, 779–782. Barbarese E., Nielson M. L., and Carson J. H. (1983) The effect of the shiverer mutation on myelin basic protein expression in homozygous and heterozygous mouse brain. J. Neurochem. 40, 1680–1686. Benjamins J. A. (1984) Protein metabolism of oligodendroglial cells in vivo, in Oligodendroglia ( W. T. Norton, ed), pp. 87–124. Plenum Press, New York . Bernier L., Alvarez F., Norgard E. M., Raible D. W., Mentaberry A., Schembri J. G., Sabatini D. D., and Colman D. R. (1987) Molecular cloning of a 2',3'-cyclic nucleotide 3'-phosphodies-terase: mRNAs with different 5' ends encode the same set of proteins in nervous and lymphoid tissues. J. Neurosci. (in press). Billings-Gagliardi S. and Adcock L. (1981) Hypomyelinated mutant mice. IV. Peripheral myelin in jpmsd. Brain Res. 225, 309–317. Billings-Gagliardi S., Adcock, L. H., Schwing, G. B., and Wolf M. K. (1980) Hypomyelinated mutant mice. II. Myelination in vitro. Brain Res. 200, 135–150. Bourre J. M., Jacque C., Delassale A., Nguyen-Lagros J., Dumont O., Lachapelle F., Raoul M., Alvarez C., and Baumann N. (1980) Density profile and basic protein measurements in the myelin range of pariculate material from normal developing mouse brain and from neurological mutants. J. Neurochem. 35, 458–464. Brostoff S., Greenfield S., and Hogan E. L. (1977) The differentiation of synthesis from incorporation of basic protein in quaking mutant mouse myelin. Brain Res. 120, 571–520. Campagnoni A. T. and Hunkeler M. J. (1980) Synthesis of the myelin proteolipid protein in the developing mouse brain. J. Neurobiol. 11, 355–364. Campagnoni A. T. and Macklin W. B. (1988) Cellular and molecular aspects of myelin protein gene expression. Mol. Neurobiol. (in press). Campagnoni A. T., Campagnoni C. W., Huang A. L., and Sam-pugna J. (1972) Developmental changes in the basic proteins of normal and jimpy mouse brain. Biochem. Biophys. Res. Commun. 46, 700–707. Campagnoni A. T., Campagnoni C. W., Dutton G. R., and Cohen J. (1976) A regional study of developing rat brain: the accumulation and distribution of proteolipid proteins. J. Neuro-biol. 7, 313–324. Campagnoni A. T., Campagnoni C. W., Bourre J.-M., Jacque C., and Baumann N. (1984) Cell-free synthesis of myelin basic proteins in normal and dysmyelinating mutant mice. J. Neurochem. 42, 733–739. Campagnoni A. T., Hunkeler M. J., and Moskaitis J. E. (1987a) Translational regulation of myelin basic protein synthesis. J. Neurosci. Res. 17, 102–110. Campagnoni A. T., Sorg B. A., Roth H. J., Kronquist K., Newman S. L., Kitamura K., Campagnoni C. W., and Crandall B. F. (1987b) Expression of myelin protein genes in the developing brain. J. Physiol.(Paris) (in press). Campagnoni C. W., Carey G. D., and Campagnoni A. T. (1978) Synthesis of myelin basic proteins in the developing mouse brain. Arch. Biochem. Biophys. 190, 118–125. Carnow T. B., Carson J. H., Brostoff S. W., and Hogan E. L. (1984) Myelin basic protein gene expression in quaking, jimpy, and myelin synlhesis-deficient mice. Dev. Biol. 106, 38–44. Carson J. H., Nielson M. L., and Barbarese E. (1983) Developmental regulation of myelin basic protein expression in mouse brain. Dev. Biol. 96, 485–492. Chan D. S. and Lees M. B. (1974) Gel electrophoresis studies of bovine brain white matter proteolipid and myelin proteins. Biochemistry 13, 2704–2712. Chemoff G. (1981) Shiverer: an autosomal recessive mutant mouse with myelin deficiency. J. Hered. 72, 128. Colman D. R., Kreibich G., Frey A. B., and Sabatini D. D. (1982) Synthesis and incorporation of myelin polypeptides into CNS myelin. J. Cell Biol. 95, 598–608. Dautigny A., Alliel P. M., Nussbaum J. L., and Jolles P. (1983) Cell-free synthesis of rat brain myelin proteolipids and their identification by immunoprecipitation. Biochem. Biophys. Res. Commun. 110, 432–437. Dautigny A., Alliel P. M., D'Auriol L., Pham Dinh D., Nussbaum J.-L., Galibert F., and Jolles P. (1985) Molecular cloning and nucleotide sequence of a cDNA clone coding for rat brain myelin proteolipid. FEBS Lett. 188, 33–36. Dautigny A., Mattei M.-G., Morello D., Alliel P. M., Pham-Dinh D., Amar L., Arnaud D., Simon D., Mattei J.-F., Guenet J.-L., Jolles P., and Avner P. (1986) The structural gene coding for myelin-associated proteolipid protein is mutated in jimpy mice. Nature 321, 867–869. de Ferra F., Engh H., Hudson L., Kamholz J., Puckett C., Molin-eaux S., and Lazzarini R. A. (1985) Alternative splicing accounts for the four forms of myelin basic protein. Cell 43, 721–727. Delassale A., Zalc B., Lachapelle R., Raoul M., Collier P., and Jacque C. (1981) Regional distribution of myelin basic protein in the CNS quaking, jimpy, and normal mice during developmental and aging. J. Neurosci. Res. 6, 303–313. Diehl H.-J., Schaich M., Budzinski R.-M., and Stoffel W. (1986) Individual exons encode the integral membrane domains of human myelin proteolipid protein. Proc. Natl. Acad. Sci. USA 83, 9807–9811. Doolittle D. P. and Schweikart K. M. (1977) Myelin deficient, a new neurological mutant in the mouse. J. Hered. 68, 331–332. Doolittle D. P., Baumann N., and Chemoff G. (1981) Allelism of two myelin deficiency mutations in the mouse. J. Hered. 72, 285. Drummond R. J. (1979) Purification of 2',3'-cyclic nucleotide 3'-phosphohydrolase from bovine brain by immunoaffinity chromatography: further biochemical characterization of the protein. J. Neurochem. 33, 1143–1150. Eicher E. M. and Hoppe P. C. (1973) Use of chimeras to transmit lethal genes in the mouse and to demonstrate allelism of the two X-linked male lethal genes jp and. msd. J. Exp. Zool. 183, 181–184. Einstein E., Dalai K. B., and Csejtey J. (1970) Biochemical maturation of the central nervous system. II. Protein and proteolytic enzyme changes. Brain Res. 18, 35–49. Eng L. F., Chao F. C., Gerstl B., Pratt D., and Tavaststjerna M. G. (1968) The maturation of human white matter: fractionation of the myelin membrane proteins. Biochemistry 7, 4455–4465. Fagg G. E. (1979) The quaking mouse: regional variation content and protein composition of myelin isolated from the central nervous system. Neuroscience 4, 973–978. Fahim S. and Riordan J. R. (1986) Lipophilin (PLP) gene in X-linked myelin disorders. J. Neurosci. Res. 16, 303–310. Frail D. E. and Braun P. E. (1984) Two developmentally regulated messenger RNAs differing in their coding region may exist for the myelin-associated glycoprotein. J. Biol. Chem. 259, 14857–14862. Frail D. E. and Braun P. E. (1985) Abnormal expression of the myelin-associated glycoprotein in the central nervous system of dysmyelinating mutant mice. J. Neurochem. 45, 1071–1075. Friedrich V. L. (1974) The myelin deficit in quaking mice. Brain Res. 82, 168–178. Gardinier M. V. and Macklin W. B. (1988) Myelin proteolipid protein gene expression in jimpy (jp) and jpmsd mice. J. Neuro-chem. (in press). Gardinier M. V., Macklin W. B., Diniak A. J., and Deininger P. L. (1986) Characterization of myelin proteolipid mRNAs in normal and jimpy mice. Mol. Cell. Biol. 6, 3755–3762. Ginalski-Winkelmann H., Guillermina A., and Matthieu J.-M. (1983) In vitro myelin basic protein synthesis in the PNS and CNS of myelin deficient (mld) mutant mice. Brain Res. 277, 386–388. Greenfield S., Norton W. T., and Morell P. (1971) Quaking mouse: isolation and characterization of myelin protein. J. Neuro-chem. 18, 2119–2128. Greenfield S., Brostoff S., and Hogan E. (1977) Evidence for defective incorporation of proteins in myelin of the quaking mutant mouse. Brain Res. 120, 507–515. Greenfield S., William N. I., White M., Brostoff S. W., and Hogan E. L. (1979) Proteolipid protein: synthesis and assembly into quaking mouse myelin. J. Neurochem. 32, 1647–1651. Holley J. A. and Yu R. K. (1987) Localization of glycoconjugates recognized by the HNK-1 antibody in mouse and chick embryos during early neural development. Dev. Neurosci. 9, 105–119. Hudson L. D., Berndt J. A., Puckett C., Kozak C. A., and Lazzarini R. A. (1987) Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse. Proc. Natl. Acad. Sci. USA 84, 1454–1458. Hunkapiller T. and Hood L. (1986) The growing immunoglobulin gene superfamily. Nature 323, 15–16. Inuzuki T., Johnson D., and Quarles R. H. (1987) Myelin-asso-ciated glycoprotein in the central and peripheral nervous system of quaking mice. J Neurochem. 49, 597–602. Jacque C., Delassalle A., Raoul M., and Baumann N. (1983) Myelin basic protein deposition in the optic and sciatic nerves of dysmyelinating mutants quaking, jimpy, trembler, MLD and shiverer during development. J. Neurochem. 41, 1335–1340. Kamholz J., de Ferra F., Puckett C., and Lazzarini R. (1986) Identification of three forms of human myelin basic protein by cDNA cloning. Proc. Natl. Acad. Sci. USA 83, 4962–4966. Karin N. J. and Waehneldt T. V. (1985) Biosynthesis and insertion of Wolfgram protein into optic nerve membranes. Neurochem. Res. 10, 897–907. Kerner A.-L. and Carson J. H. (1984) Effect of the jimpy mutation on expression of myelin proteins in heterozygous and hemizy-gous mouse brain. J. Neurochem. 43, 1706–1715. Kimura M., Inoko H., Katsuki M., Ando A., Sato T., Hirose T., Takashima H., Inayama S., Okano H., Takamatsu K., Miko-shiba K., Tsukada Y., and Watanabe I. (1985) Molecular genetic analysis of myelin-deficient mice: shiverer mutant mice show deletion in gene(s) coding for myelin basic protein. J. Neurochem. 44, 692–696. Knapp P. E., Skoff R. P., and Redstone D. W. (1986) Oligoden-droglial cell death in jimpy mice: an explanation for the myelin deficit. J. Neurosci. 6, 2813–2822. Kronquist K. E., Crandall B. E., Macklin W. B., and Campagnoni A. T. (1987) Expression of myelin proteins in the developing human spinal cord: cloning and sequencing of human proteolipid protein cDNA. J. Neurosci. Res. 18, 395–401. Kruse F., Mailhammer R., Wernecke H., Faissner A., Sommer I., Gordis C., and Schachner M. (1984) Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1. Nature 311, 153–155. Kruse F., Keilhauer G., Faissner A., Timpl R., and Schachner M. (1985) The J1 glycoprotein-A novel nervous system cell adhesion molecule of the L2/HNK1 family. Nature 316, 146–148. Kurihara T. and Tsukada Y. (1967) The regional and subcellular distribution of 2',3'-cyclic nucleotide 3'-phosphohydrolase in the central nervous system. J. Neurochem. 14, 1167–1174. Kurihara T. and Tsukada Y. (1968) 2',3'-Cyclic nucleotide 3'-phos-phohydrolase in the developing chick brain and spinal cord. J. Neurochem. 15, 827–832. Kurihara T., Nussbaum J. L., and Mandel P. (1969)2,3'-Cyclic nucleotide 3'-phosphohydrolase in the brain of the "jimpy" mouse, a mutant with deficient myelination. Brain Res. 13, 401–403. Kurihara T., Nussbaum J. L., and Mandel P. (1970) 2',3'-Cyclic nucleotide 3'-phosphohydrolase in brains of mutant mice with deficient myelination. J. Neurochem. 17, 993–997. Kurihara T., Fowler A. V., and Takahashi Y. (1987) cDNA cloning and amino acid sequence of bovine brain 2',3'-cyclic-nucleo-tide 3'-phosphodiesterase. J. Biol. Chem. 262, 3256–3261. Lai C., Brow M. A., Nave K.-A., Noronha A. B., Quarles R. H., Bloom F. E., Milner R. J., and Sutcliffe J. G. (1987) Two forms of lB236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing. Proc. Natl. Acad. Sci. USA 84, 4227–4341. Lees M. B. (1982) Proteolipids. Scand. J. Immunol. 15(9), 147–166. Lees M. B. and Macklin W. B. (1988) Myelin proteolipid protein, in Functional and Clinical Aspects of Neuronal and Glial Proteins: Neurobiological Research, Volume 2 ( R. M. Cohen, eds), pp. 267–294. Academic Press, Oilando , Florida . Lees M. B. and Sapirstein V. S. (1983) Myelin-associated enzymes, in Handbook of Neurochemistry, Vol. 4, 2nd ed. ( A. Lajtha, ed), pp. 435–460. Plenum, New York . Lepage P., Helynck G., Chu J.-Y., Luu B., Sorokine O., Trifilieff E., and Van Dorsselaer A. (1986) Purification and characterization of minor brain proteolipids: use of fast atom bombardment-mass spectrometery for peptide sequencing. Biochi-mie 68, 669–686. Lerner P., Campagnoni A. T., and Sampugna J. (1974) Proteolipids in the developing brains of normal mice and myelin deficient mutants. J. Neurochem. 22, 163–170. Macklin W. B. and Weill C. L. (1985) Appearance of myelin proteins during development in the chick central nervous system. Dev. Neurosci. 7, 170–178. Macklin W. B., Oberfield E., and Lees M. B. (1983) Electroblot analysis of rat myelin proteolipid protein and basic protein during development. Dev. Neurosci. 6, 161–168. Macklin W. B., Gardinier M. V., King K. D., and Kampf K. (1987a) An AG → GG transition at a splice site in the myelin proteolipid protein gene in jimpy mice results in the removal of an exon. FEBS Lett. 223, 417–421. Macklin W. B., Campagnoni C. W., Deininger P. L., and Gardinier M. V. (1987b) Structure and expression of the mouse myelin proteolipid protein gene. J. Neurosci. Res. 18, 383–394. Magno-Sumbilla C. and Campagnoni A. T. (1977) Factors affecting the electrophoretic analysis of myelin proteins: application to changes occurring during brain development. Brain Res. 126, 131–148. Martini R. and Schachner M. (1986) Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve. J. Cell Biol. 103, 2439–2448. Mattei M. G., Alliel P. M., Dautigny A., Passage E., Pham-Dinh D., Mattei J. F., and Jolles P. (1986) The gene encoding for the major brain proteolipid (PLP) maps on the q-22 band of the human X chromosome. Hum. Genet. 72, 352–353. Matthieu J.-M., Brady R. O., and Quarles R. H. (1974) Development change in a myelin-associated glycoprotein comparative study in rodents. Dev. Biol. 37, 146–152. Matthieu J.-M., Roch J.-M., Omlin F. X., Rambaldi I., Almazan G., and Braun P. E. (1986) Myelin instability and oligoden-drocyte metabolism in myelin-deficient mutant mice. J. Cell Biol. 103, 2673–2682. McGarry R. C., Helfand S. L., Quarles R. H., and Roder J. C. (1983) Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1. Nature 306, 376–378. Meier C. and MacPike A. D. (1970) A neurological mutation (msd) of the mouse causing a deficiency of myelin synthesis. Exp. Brain Res. 10, 512–525. Mentaberry A., Adesnik M., Atehison M., Norgard E. M., Alvarez F., Sabatini D. D., and Colman D. R. (1986) Small basic proteins of myelin from central and peripheral nervous systems are encoded by the same gene. Proc. Natl. Acad. Sci. USA 83, 1111–1114. Mikoshiba K., Nagaike K., Aoki E., and Tsukada Y. (1979) Biochemical and immunohistochemical studies on dysmyelina-tion of quaking mutant mice in vivo and in vitro. Brain Res. 177, 287–299. Mikoshiba K., Kohasaka S., Hayakawa T., Takamatsu K., and Tsukada Y. (1985) Immunohistochemical localization of 2',3-cyclic nucleotide 3'-phosphodiesterase and myelin basic protein in the central nervous system of the jimpy and the normal mouse. J. Neurochem. 44, 686–691. Milner R. J., Lai C., Nave K.-A., Lenoir D., Ogata J., and Sutcliffe J. G. (1985) Nucleotide sequences of two mRNAs for rat brain myelin proteolipid protein. Cell 42, 931–939. Miskimins R. and Yu R. K. (1986) Developmental expression of myelin basic protein mRNA in a hypermyelinating mouse. J. Neurosci. Res. 16, 219–225. Molineaux S. M., Engh H., de Ferra F., Hudson L., and Lazzarini R. A. (1986) Recombination within the myelin basic protein gene created the dysmyelinating shiverer mouse mutant. Proc. Natl. Acad. Sci. USA 83, 7542–7546. Monge M., Kadiiski D., Jacque C. M., and Zalc B. (1986) Oligo-dendroglial expression and deposition of four major myelin constituents in the myelin sheath during development: an in vivo study. Dev. Neurosci. 8, 222–235. Morell P., Greenfield S., Costantino-Ceccarini E., and Wisniewski H. (1972) Changes in the protein composition of mouse brain myelin during development. J. Neurochem. 19, 2545–2554. Morello D., Dautigny A., Pham-Dinh D., and Jolles P. (1986) Myelin proteolipid protein (PLP and DM-20) transcripts are deleted in jimpy mutant mice. EMBO J. 5, 3489–3493. Naismith A. L., Hoffman-Chudzik E., Tsui L.-C., and Riordan J. R. (1985) Study of the expression of myelin proteolipid protein (lipophilin) using a cloned complementary DNA. Nucleic Acids Res. 13, 7413–7425. Nave K.-A., Lai C., Bloom F. E., and Milner R. J. (1986) Jimpy mutant mouse: a 74 base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing. Proc. Natl. Acad. Sci. USA 83, 9264–9268. Nave K.-A., Lai C., Bloom F. E., and Milner R. J. (1987a) Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of CNS myelin. Proc. Natl. Acad. Sci. USA 84, 5665–5669. Nave K.-A., Bloom F. E., and Milner R. J. (1987) A single nucleotide difference in the gene for myelin proteolipid protein defines the jimpy mutation in mouse. J. Neurochem. 49, 1873–1877. Newman S. L., Kitamura K., and Campagnoni A. T. (1987a) Identification of a cDNA coding for a fifth form of myelin basic protein in mouse. Proc. Natl. Acad. Sci. USA 84, 886–890. Newman S. L., Kitamura K., Roth H. J., Kronquist K., Kerlero, DE Rosbo N., Crandall B. F., and Campagnoni A. T. (1987b) Differential expression of the myelin basic protein genes in mouse and human. (Abstr) J. Neurochem. 48 (Suppl), S27. Nussbaum J. L. and Mandel P. (1973) Brain proteolipids in neurological mutant mice. Brain Res. 61, 295–310. Okano H., Miura M., Moriguchi A., Ikenaka K., Tsukada Y., and Mikoshiba K. (1987) Inefficient transcription of the myelin basic protein gene possibly causes hypomyelination in my-elin-deficient mutant mice. J. Neurochem. 48, 470–476. Olafson R. W., Drummond G. I., and Lee J. F. (1969) Studies on 2',3'-cyclic nucleotide-3'-phosphohydrolase from brain. Can. J.Biochem. 47, 961–966. Poduslo J. F., Quarles R. H., and Brady R. O. (1976) External labeling of galactose in surface membrane glycoproteins of the intact myelin sheath. J. Biol. Chem. 251, 153–158. Popko B., Puckett C., Lai E., Shine H. D., Readhead C., Takahashi N., Hunt, S. W., Sidman, R. L., and Hood L. (1987) Myelin deficient mice: expression of myelin basic protein and generation of mice with varying levels of myelin. Cell 48, 713–721. Quarles R. H. (1979) Glycoproteins in myelin and myelin related membranes, in Myelin Chemistry and Biology ( G. Hashim, ed), pp. 55–77. Alan R. Liss, New York . Quarles R. H. (1983) Myelin-associated glycoprotein in development and disease. Dev. Neurosci. 6, 285–303. Quarles R. H., Barbarash G. R., Figlewicz D. A., and McIntyre L. J. (1983) Purification of partial characterization of the myelin-associated glycoprotein from adult rat brain. Biochim. Biophys. Acta 757, 140–143. Readhead C., Popko B., Takahashi N., Shine H. D., Saavedra R. A., Sidman R. L., and Hood L. (1987) Expression of a myelin basic protein gene in transgenic shiverer mice: correction of the dysmyelinating phenotype. Cell 48, 703–712. Roach A., Boylan K., Horvath S., Prusiner S. B., and Hood L. (1983) Characterization of cloned cDNA representing rat myelin basic protein: absence of expression in brain of shiverer mutant mice. Cell 42, 799–806. Roach A., Takahashi N., Pravtcheva D., Ruddle F., and Hood L. (1985) Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice. Cell 42, 149–155. Roch J.-M., Brown-Luedi M., Cooper B. J., and Matthieu J.-M. (1986) Mice heterozygous for the mld mutation have intermediate levels of myelin basic protein mRNA and its translation products. Mol. Brain Res. 1, 137–144. Roth H. J., Hunkeler M. J., and Campagnoni A. T. (1985) Expression of myelin basic protein genes in several dysmyelinating mouse mutants during early postnatal brain development. J. Neurochem. 45, 572–580. Roth H. J., Kronquist K., Pretorius P. J., Crandall P. J., Crandall B. F., and Campagnoni A. T. (1986) Isolation and characterization of a cDNA coding for a novel human 17.3 K myelin basic protein (MBP) variant. J. Neurosci. Res. 16, 227–238. Roth H. J., Kronquist K.E., Kerlero, DE Rosbo N., Crandall B. F., and Campagnoni A. T. (1987) Evidence for the expression of four myelin basic protein variants in the developing human spinal cord through cDNA cloning. J. Neurosci. Res. 17, 321–328. Salzer J. L., Holmes W. P., and Colman D. R. (1987) The amino acid sequences of the myelin-associated glycoproteins: homol-ogy to the immunoglobulin gene superfamily. J. Cell Biol. 104, 957–965. Sarlieve L. L., Farooqui A. A., Rebel G., and Mandel P. (1976) Arylsulphatase A and 2',3'-cyclic nucleotide 3'-phosphohydro-lase activities in the brains of myelin deficient mutant mice. Neuroscience 1, 519–522. Saxe D. F., Takahashi N., Hood L., and Simon M. I. (1985) Localization of the human myelin basic protein gene (MBP) to region 18q22 → qter by in situ hybridization. Cytogenel. Cell Genet. 39, 246–249. Scott J. M., Wilson P., Dinn J. J., and Weir D. G. (1981) Pathogen-esis of subacute combined degeneration: a result of methyl group deficiency. Lancet 2, 334–337. Shashoua V. E., Jungalwala G. B., Chou D. K. H., and Moore M. E. (1986) Sulfated glucuronyl glycoconjugates in ependy-mins offish and human CSF. (Abstr). Trans. Am. Soc. Neurochem. 17, 148. Sidman R. L., Dickie M. M., and Appel S. H. (1964) Mutant mice (quaking and jimpy) with deficient myelination in the central nervous system. Science 144, 309–310. Sidman R. L., Conover D. S., and Carson J. H. (1985) Shiverer gene maps near the distal end of chromosome 18 in the house mouse. Cytogenet. Cell Genet. 39, 241–245. Small D. H., Carnegie P. R., and Anderson, R. M (1981) Cyclo-leucine-induced vacuolation of myelin is associated with inhibition of protein methylation. Neurosci. Lett. 21, 287–292. Sorg B. J. A., Agrawal D., Agrawal H. C., and Campagnoni A. T. (1986) Expression of myelin proteolipid protein and basic protein in normal and dysmyelinating mutant mice. J. Neuro-chem. 46, 379–387. Sorg B. J. A., Smith M. M., and Campagnoni A. T. (1987) Developmental expression of the myelin proteolipid protein and basic protein mRNAs in normal and dysmyelinating mutant mice. J. Neurochem. 49, 1146–1154. Sparkes R. S., Mohandas T., Heinzmann C., Roth H. J., Klisak I., and Campagnoni A. T. (1987) Assignment of the myelin basic protein gene to human chromosome 18q22-qter. Hum. Genet. 75, 147–150. Sprinkle T. J., Zaruba M. E., and McKhann G. M. (1978) Activity of 2',3'-cyclic-nucleotide 3'-phosphodiesterase in regions of rat brain during development: quantitative relationship to myelin basic protein. J. Neurochem. 30, 309–314. Sprinkle T. J., Grimes M. J., and Eller A. G. (1980) Isolation of 2',3'-cyclic nucleotide 3'-phosphodiesterase from human brain. J. Neurochem. 34, 880–887. Sternberger N. H., Quarles R. H., Itoyama Y., and Webster, H. deF. (1979) Myelin-associated glycoprotein demonstrated immu-nocytochemically in myelin and myelin-forming cells of developing rat. Proc. Natl. Acad. Sci. USA 76, 1510–1514. Sutcliffe J. G. (1987) The genes for myelin. Trends Genet. 3, 73–76. Sutcliffe J. G., Milner R. J., Shinnick T. M., and Bloom F. E. (1983) Identifying the protein products of brain-specific genes with antibodies to chemically synthesized peptides. Cell 33, 671–682. Takahashi N., Roach A., Teplow D. B., Prusiner S. B., and Hood L. (1985) Cloning and characterization of the myelin basic protein gene from mouse: one gene can encode both 14 kd and 18.5 kd MBPs by alternate use of exons. Cell 42, 139–148. Tennekoon G. I., Cohen S. R., Price D. L., and McKhann G. M. (1977) Myelinogenesis in optic nerve: a morphological, auto-radiographic, and biochemical analysis. J. Cell Biol. 72, 604–616. Trapp B. D. and Quarles R. H. (1982) Presence of the myelin-associated glycoprotein correlates with alterations in the periodicity of peripheral myelin. J. Cell Biol. 92, 877–882. Trapp B. D., Quarles R. H., and Griffin J. W. (1984) Myelin-associated glycoprotein and myelinating Schwann cell-axon interaction in chronic β,β'-iminodipropionitrile neuropathy. J. Cell. Biol. 98, 1272–1278. Trifilieff E., Skalidis G., Helynck G., Lepage P., Sorokine O., Van Dorsselaer A., and Luu B. (1985) Structural data about the myelin proteolipid of apparent molecular weight 20 kDa (DM-20). C. R. Acad. Sci. [ III] 241–246. Triflieff E., Luu B., Nussbaum J. L., Roussel G., Espinosa, DE Los Monteros A., Sabatier J. M., and Van Rietschoten J. (1986) A specific immunological probe for the major myelin proteolipid: confirmation of a deletion in DM-20. FEBS Lett. 198, 235–239. Waehneldt T. V. (1975) Ontogenetic study of a myelin-derived fraction with 2':3'-cyclic nucleotide 3'-phosphohydrolase activity higher than that of myelin. Biochem. J. 151, 435–437. Webster, H. deF., Palkovits C. G., Stoner G. L., Favilla J. T., Frail D. E., and Braun P. E. (1983) Myelin-associated glycoprotein: electron microscopic immunocytochemical localization in compact developing and adult central nervous system myelin. J. Neurochem. 41, 1469–1479. Willard H. F. and Riordan J. R. (1985) Assignment of the gene for myelin proteolipid protein to the X chromosome: implications for X-linked myelin disorders. Science 230, 940–942. Wisniewski H. and Morell P. (1971) Quaking mouse: ultrastruc-tural evidence for arrest of myelinogenesis. Brain Res. 29, 63–73. Wolf M. K., Kardon G. B., Adcock L. H., and Billings-Gagliardi S. (1983) Hypomyelinated mutant mice. V. Relationship between jp and jpmsd re-examined on identical genetic backgrounds. Brain Res. 271, 121–129. Wolfgram F. (1966) A new proteolipid fraction of the nervous system—isolation and amino acid analyses. J. Neurochem. 13, 461–470. Yanagisawa K. and Quarles R. H. (1986) Jimpy mice: quantitation of myelin-associate glycoprotein and other proteins. J. Neurochem. 47, 322–325. Yu Y.-T. and Campagnoni A. T. (1982) In vitro synthesis of the four mouse myelin basic proteins: evidence for the lack of a metabolic relationship. J. Neurochem. 39, 1559–1568. Zeller N. K., Hunkeler M. J., Campagnoni A. T., Sprague J., and Lazzarini R. A. (1984) Characterization of mouse myelin basic protein messenger RNAs with a myelin basic protein cDNA clone. Proc. Natl. Acad. Sci. USA 81, 18–22. Citing Literature Volume51, Issue1July 1988Pages 1-14 ReferencesRelatedInformation
Referência(s)