Laboratory manifestations of polymyositis/ dermatomyositis
1988; Elsevier BV; Volume: 6; Issue: 2 Linguagem: Inglês
10.1016/0738-081x(88)90051-x
ISSN1879-1131
Autores Tópico(s)Heterotopic Ossification and Related Conditions
ResumoThe laboratory is important in both the diagnosis and treatment of dermatomyositis (DM) and polymyositis (PM). Serum or urine levels of the various muscle constituents released as a result of muscle injury are monitored, assisting in patient management by providing evidence of muscle damage (Table 9-1). The factors commonly monitored include enzymes (creatine kinase [CK], aldolase, the transaminases, and lactic dehydrogenase [LDH]), as well as myoglobin and creatine. In addition, autoantibodies can be detected in most patients with PM/DM, providing evidence of autoimmunity and assisting in diagnosis and patient classification.
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