Mutations of ANK3 identified by exome sequencing are associated with autism susceptibility
2012; Wiley; Volume: 33; Issue: 12 Linguagem: Inglês
10.1002/humu.22174
ISSN1098-1004
AutoresCheng Bi, Jinyu Wu, Tao Jiang, Qi Liu, Wanshi Cai, Ping Yu, Tao Cai, Mei Zhao, Yong‐hui Jiang, Zhong Sheng Sun,
Tópico(s)Virology and Viral Diseases
ResumoHuman MutationVolume 33, Issue 12 p. 1635-1638 Brief Report Mutations of ANK3 identified by exome sequencing are associated with autism susceptibility† Cheng Bi, Cheng Bi Institute of Psychology, Chinese Academy of Sciences, Beijing, P. R. China Graduate University of Chinese Academy of Sciences, Beijing, P. R. China These authors contributed equally to this workSearch for more papers by this authorJinyu Wu, Jinyu Wu Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. China These authors contributed equally to this workSearch for more papers by this authorTao Jiang, Tao Jiang Beijing Genomics Institute-Shenzhen, Shenzhen, P. R. ChinaSearch for more papers by this authorQi Liu, Qi Liu Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. ChinaSearch for more papers by this authorWanshi Cai, Wanshi Cai Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. ChinaSearch for more papers by this authorPing Yu, Ping Yu Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. ChinaSearch for more papers by this authorTao Cai, Tao Cai Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. China Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, P. R. ChinaSearch for more papers by this authorMei Zhao, Mei Zhao Institute of Psychology, Chinese Academy of Sciences, Beijing, P. R. ChinaSearch for more papers by this authorYong-hui Jiang, Corresponding Author Yong-hui Jiang [email protected] Department of Pediatrics and Neurobiology, Duke University School of Medicine, Durham, North Carolina, USA Yong-hui Jiang, Durham, NC27710, USA Zhong Sheng Sun, Beichen West Road, Chao Yang District, Beijing 100101, ChinaSearch for more papers by this authorZhong Sheng Sun, Corresponding Author Zhong Sheng Sun [email protected] Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. China Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, P. R. China Yong-hui Jiang, Durham, NC27710, USA Zhong Sheng Sun, Beichen West Road, Chao Yang District, Beijing 100101, ChinaSearch for more papers by this author Cheng Bi, Cheng Bi Institute of Psychology, Chinese Academy of Sciences, Beijing, P. R. China Graduate University of Chinese Academy of Sciences, Beijing, P. R. China These authors contributed equally to this workSearch for more papers by this authorJinyu Wu, Jinyu Wu Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. China These authors contributed equally to this workSearch for more papers by this authorTao Jiang, Tao Jiang Beijing Genomics Institute-Shenzhen, Shenzhen, P. R. ChinaSearch for more papers by this authorQi Liu, Qi Liu Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. ChinaSearch for more papers by this authorWanshi Cai, Wanshi Cai Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. ChinaSearch for more papers by this authorPing Yu, Ping Yu Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. ChinaSearch for more papers by this authorTao Cai, Tao Cai Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. China Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, P. R. ChinaSearch for more papers by this authorMei Zhao, Mei Zhao Institute of Psychology, Chinese Academy of Sciences, Beijing, P. R. ChinaSearch for more papers by this authorYong-hui Jiang, Corresponding Author Yong-hui Jiang [email protected] Department of Pediatrics and Neurobiology, Duke University School of Medicine, Durham, North Carolina, USA Yong-hui Jiang, Durham, NC27710, USA Zhong Sheng Sun, Beichen West Road, Chao Yang District, Beijing 100101, ChinaSearch for more papers by this authorZhong Sheng Sun, Corresponding Author Zhong Sheng Sun [email protected] Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, P. R. China Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, P. R. China Yong-hui Jiang, Durham, NC27710, USA Zhong Sheng Sun, Beichen West Road, Chao Yang District, Beijing 100101, ChinaSearch for more papers by this author First published: 03 August 2012 https://doi.org/10.1002/humu.22174Citations: 83 † Communicated by Hamish S. Scott Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Autism spectrum disorders (ASDs) are common neurodevelopmental disorders with a strong genetic etiology. However, due to the extreme genetic heterogeneity of ASDs, traditional approaches for gene discovery are challenging. Next-generation sequencing technologies offer an opportunity to accelerate the identification of the genetic causes of ASDs. Here, we report the results of whole-exome sequence in a cohort of 20 ASD patients. 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Citing Literature Supporting Information Additional Supporting information may be found in the online version of this article Filename Description humu_22174_sm_SuppInfo.pdf749.1 KB Supporting Information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume33, Issue12December 2012Pages 1635-1638 ReferencesRelatedInformation
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