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Autoimmune Hemolytic Anemia as the Herald State of Hodgkin's Disease

1966; American College of Physicians; Volume: 65; Issue: 4 Linguagem: Inglês

10.7326/0003-4819-65-4-761

1539-3704

A. J. Bowdler,

Multiple and Secondary Primary Cancers

Case Studies1 October 1966Autoimmune Hemolytic Anemia as the Herald State of Hodgkin's DiseaseA. J. BOWDLER, M.D., I. W. GLICK, M.B.A. J. BOWDLER, M.D.Search for more papers by this author, I. W. GLICK, M.B.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-4-761 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAnemia is a common manifestation of Hodgkin's disease; Levinson, Walter, Wintrobe, and Cartwright (1) found mild or moderate anemia in 52% of patients before therapy and showed that moderate anemia, while not necessarily a late manifestation of the disease, was usually associated with short survival and a poor prognosis. Such anemia has been shown to be the result of the shortening of the survival time of the red cells together with an inadequate erythropoietic response so that the bone marrow is unable to compensate for the increased rate of red cell destruction (2). Frankly hemolytic anemia has also been described...References1. LEVINSONWALTERWINTROBECARTWRIGHT BBAMWGE: A clinical study in Hodgkin's disease. Arch. Intern. Med. (Chicago) 99: 519, 1957. CrossrefGoogle Scholar2. GIANNOPOULOSBERGSAGEL PPDE: The mechanism of the anemia associated with Hodgkin's disease. Blood 14: 856, 1959. CrossrefMedlineGoogle Scholar3. HOLLERPASCHKIS GK: Zur Klinik der splenomegalen Lymphogranulomatose. Wien. Arch. Inn. Med. 14: 149, 1927. Google Scholar4. WATSON CJ: Hemolytic jaundice and macrocytic hemolytic anemia: certain observations in a series of 35 cases. Ann. Intern. Med. 12: 1782, 1939. LinkGoogle Scholar5. DAVIS LJ: Symptomatic haemolytic anaemia; a report of four cases. Edin. Med. J. n.s. 51: 70: 1944. 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CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: A. J. BOWDLER, M.D.; I. W. GLICK, M.B.Affiliations: London,From the University College Hospital Medical School, London, England.Requests for reprints should be addressed to A. J. Bowdler, M.D., Medical Unit, University College Hospital Medical School, University St., London W. C. 1, England. 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