Synthesis and in vitro photodynamic activity of novel galactose-containing phthalocyanines
2005; Elsevier BV; Volume: 46; Issue: 9 Linguagem: Inglês
10.1016/j.tetlet.2004.12.137
ISSN1873-3581
AutoresPriscilla P. S. Lee, Pui‐Chi Lo, Elaine Y. M. Chan, Wing‐Ping Fong, W.H. Ko, Dennis K. P. Ng,
Tópico(s)Nanoplatforms for cancer theranostics
ResumoA novel series of silicon(IV) phthalocyanines with one or two axial acetal-protected galactose substituent(s) have been prepared by typical substitution reactions. The compounds exhibit a high photodynamic activity against HepG2 human hepatocarcinoma cells with IC50 values down to 0.10 μM.
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