The Influence of Polyelectrotytes on the Formation and Phase Transformation of Amorphous Calcium Phosphate
2003; Trans Tech Publications; Volume: 240-242; Linguagem: Inglês
10.4028/www.scientific.net/kem.240-242.453
ISSN1662-9809
AutoresH. Füredi‐Milhofer, P. Bar-Yosef, R. Govrin-Lippman, Nissim Garti,
Tópico(s)Polymer Surface Interaction Studies
ResumoA promising route to the fabrication of biomimetic coatings for artificial implants is the deposition of organic/inorganic composite materials consisting of polyelectrolyte multilayers alternating with layers of “in situ” grown calcium phosphate crystals. To facilitate understanding of the underlying mechanisms, in this paper we discuss the influence of polyelectrolytes (PEs), polystyrene sulfonate (PSS), poly-l-lysine (PLL), and poly-l-glutamic acid (PGA) on the formation and properties of amorphous calcium phosphate (ACP) and on the nucleation and growth morphology of the crystalline phase. pH vs time curves revealed three distinct precipitation events, i.e., (I) precipitation of ACP, (II) secondary precipitation of a crystalline phase upon the amorphous precursor, and (III) solution-mediated phase transformation and crystal growth. Finally, crystalline mixtures with low Ca/P molar ratios (1.39), consisting of octacalcium phosphate crystals and small amounts of apatite, were obtained. From the pH vs tim...
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