Produção Nacional
Revisado por pares
Isomorphic phenomenon of Koebner: Facts and controversies
2013; Elsevier BV; Volume: 31; Issue: 6 Linguagem: Inglês
10.1016/j.clindermatol.2013.05.012
ISSN1879-1131
AutoresCláudia Medeiros Camargo, Arles Martins Brotas, Márcia Ramos‐e‐Silva, Sueli Carneiro,
Tópico(s)Cancer and Skin Lesions
ResumoHeinrich Koebner (1838–1904) presented in a meeting in 1872 and reported in 1877 the emergence of psoriatic lesions following trauma to healthy skin areas of patients with psoriasis. Since then, the Koebner phenomenon has been the subject of research, as it offers a unique opportunity in the investigation of the disease, especially in experimental studies, when this dermatosis may be observed in all its phases. Establishing the differences between Koebner, Wolf, Renbök, reverse Koebner, pseudo-Koebner phenomena, and pathergy is sometimes unclear. We review the various aspects of the Koebner phenomenon´s clinical description and presentation, pathophysiology, histopathology, reverse phenomenon, therapeutic treatments, and prevention.
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