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Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru

1995; Elsevier BV; Volume: 59; Issue: 4 Linguagem: Inglês

10.1016/0001-706x(95)00094-u

1873-6254

Jean‐Claude Dujardin, Anne‐Laure Bañuls, Alejandro Llanos‐Cuentas, Eugenia Alvarez, Simonne DeDoncker, D. Jacquet, Dominique Le Ray, Jorge Arévalo, Michel Tibayrenc,

Insect Pest Control Strategies

During an outbreak of tegumentary leishmaniasis that developed in the 1990s in the Eastern Andean valley of Huanuco, Peru, the coexistence of Andean (uta) and sylvatic leishmaniases was suspected for ecological and geographical reasons, and sympatric sampling was carried out. Seven human isolates of Leishmania were characterized by multilocus enzyme electrophoresis, random amplification of polymorphic DNA and molecular karyotyping. The three methods identified 3 isolates as L. braziliensis, and 4 isolates as putative hybrids with characters of L. braziliensis and L. peruviana. Data from Huanuco are compared to previous results from other areas endemic for uta. Biological and epidemiological implications are discussed.