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A simple enzymatic method for the synthesis of 2-hydroxy[4-14C]estradiol

1971; Elsevier BV; Volume: 17; Issue: 1-5 Linguagem: Inglês

10.1016/s0039-128x(71)80120-4

1878-5867

Peter H. Jellinck, B.J. Brown,

Cholinesterase and Neurodegenerative Diseases

A simple method using mushroom tyrosinase in the presence of NADH to prepare 2-hydroxy[4-14C]estradiol in high yields is described. The conditions to obtain optimum amounts of this metabolite from estradiol were investigated.