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PATHOGENESIS OF SENILE CATARACT

1932; American Medical Association; Volume: 8; Issue: 1 Linguagem: Inglês

10.1001/archopht.1932.00820140107013

1538-3601

Daniel B. Kirby,

Connexins and lens biology

Cataract may be defined as any opacity of the crystalline lens. For the scope of this review senile cataract may be considered as any opacity arising in the decline of life, that is, after the adult period has been reached or passed. Duke-Elder quoted Horlacher, who found the changes of senile cataract in 65 per cent of persons between 51 and 60 years, and in 95 per cent of those above 60 (Barth, quoted by Duke-Elder). It arises at an earlier period in certain of the oriental (Kirkpatrick) races than it does in the occidental races. The literature on the pathogenesis of cataract is so voluminous that only significant and representative articles will be quoted or analyzed. Necessarily more space will be devoted to recent thought, as the older ideas have been disproved or cast aside because they give no aid to progress in the understanding of this complex biophysico-