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Model of growth and surgical treatment glioblastoma multiforme tumors localized in the motor zone of the brain-use of the direct electrocorticostimulation in the prevention of motor deficit

2014; National Library of Serbia; Volume: 61; Issue: 4 Linguagem: Inglês

10.2298/aci1404005r

2406-0887

Nikola Repac, Igor Nikolić, Miljan Mihajlović, Igor Djorić, Aleksandar Janićijević, Vuk Šćepanović, Siniša Matić, Vladimir Jovanović, Goran Tasić,

Glioma Diagnosis and Treatment

Gioblastoma multiforme localized in the motor area is the surgical challenge because of the need for more radical resection in order to extend the life of the patient, and the other due to the risk that radicalism could lead to additional-crippling neurological deficit. Method. We present a series of 26 patients with Glioblastoma multiforme localized in and around the motor area in front of the central sulcus who were hospitalized from October 2004 to February 2009. During all operations we conducted cortical electrostimulation on displayed area of the brain, to the anatomical location of M1 segment of the motor cortex. Results. Distance of the central sulcus in relation to the coronary suture, measured by magnetic resonance imaging (MRI) was 18.38 mm?9.564 mm. The volume of electricity required for a motor response was 9.26?1.286 mA(min. 7mA, max. 11mA), with increasing distance from the coronary suture the amperage required to explicit motor responses decreased (p<0.01). Conclusion: The method of direct cerebral cortex electrostimulation is simple and safe method and a binding protocol to the patient safe operation glioblastoma multiforme localized in the motor area of the brain.