Causes, Effects, and Constraints in the Genetics of Human Longevity
1998; Elsevier BV; Volume: 62; Issue: 5 Linguagem: Inglês
10.1086/301849
ISSN1537-6605
Autores Tópico(s)Birth, Development, and Health
ResumoJeanne Calment, who died recently in her 123d year, being the oldest human being alive on earth, epitomized our quest for longevity. This deeply rooted quest has been spurred by recent strides in genetics, giving rise to renewed hopes that answers to the puzzle of aging may lie close at hand, in our genome. Indeed, a survey of Jeanne Calment's ancestry revealed a striking aggregation of the longevity trait: 24% of her 55 immediate ancestors have lived to age >80 years, as compared to merely 2% of an adequately paired control group (Robine and Allard 1998).
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