THE ORIGIN OF THE WHITE BLOOD CELLS
1934; American Medical Association; Volume: 103; Issue: 20 Linguagem: Inglês
10.1001/jama.1934.02750460028008
ISSN1538-3598
Autores Tópico(s)Erythrocyte Function and Pathophysiology
ResumoSince 1870, when hematology was first established as a branch of scientific medicine by the discovery of cells in the blood stream, 1 the polemics of the problem concerning these circulating units have centered about their origin. Each decade has witnessed an increasing volume of research and an even greater variety of interpretation in an attempt to establish some concept of the histogenesis of these cells on a sound and unassailable foundation. While complete success in reaching this objective has in no sense been attained, it nevertheless is profitable to analyze, from time to time, certain fundamental aspects of the problem which seem to be influenced or clarified by recent contributions in this field. Therefore, while recognizing the difficulties inherent in the problem and the necessity of altering interpretations from time to time as additional new facts become apparent, the present discussion will seek to analyze critically some of the
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