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DivStat: A User-Friendly Tool for Single Nucleotide Polymorphism Analysis of Genomic Diversity

2015; Public Library of Science; Volume: 10; Issue: 3 Linguagem: Inglês

10.1371/journal.pone.0119851

1932-6203

Inês Soares, Ana Moleirinho, Gonçalo N. P. Oliveira, António Amorim,

Genetic Mapping and Diversity in Plants and Animals

Recent developments have led to an enormous increase of publicly available large genomic data, including complete genomes. The 1000 Genomes Project was a major contributor, releasing the results of sequencing a large number of individual genomes, and allowing for a myriad of large scale studies on human genetic variation. However, the tools currently available are insufficient when the goal concerns some analyses of data sets encompassing more than hundreds of base pairs and when considering haplotype sequences of single nucleotide polymorphisms (SNPs). Here, we present a new and potent tool to deal with large data sets allowing the computation of a variety of summary statistics of population genetic data, increasing the speed of data analysis.