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Surface Functionalization of Porous Coordination Nanocages Via Click Chemistry and Their Application in Drug Delivery

2010; Volume: 23; Issue: 1 Linguagem: Inglês

10.1002/adma.201003012

1521-4095

Dan Zhao, Songwei Tan, Daqiang Yuan, Weigang Lu, Yohannes H. Rezenom, Hongliang Jiang, Liqun Wang, Hong‐Cai Zhou,

Nanoplatforms for cancer theranostics

Advanced MaterialsVolume 23, Issue 1 p. 90-93 Communication Surface Functionalization of Porous Coordination Nanocages Via Click Chemistry and Their Application in Drug Delivery Dan Zhao, Dan Zhao Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorSongwei Tan, Songwei Tan MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, ChinaSearch for more papers by this authorDaqiang Yuan, Daqiang Yuan Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorWeigang Lu, Weigang Lu Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorYohannes H. Rezenom, Yohannes H. Rezenom Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorHongliang Jiang, Hongliang Jiang MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, ChinaSearch for more papers by this authorLi-Qun Wang, Corresponding Author Li-Qun Wang lqwang@zju.edu.cn MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China Li-Qun Wang, MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China. Hong-Cai Zhou, Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorHong-Cai Zhou, Corresponding Author Hong-Cai Zhou zhou@mail.chem.tamu.edu Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USA Li-Qun Wang, MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China. Hong-Cai Zhou, Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this author Dan Zhao, Dan Zhao Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorSongwei Tan, Songwei Tan MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, ChinaSearch for more papers by this authorDaqiang Yuan, Daqiang Yuan Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorWeigang Lu, Weigang Lu Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorYohannes H. Rezenom, Yohannes H. Rezenom Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorHongliang Jiang, Hongliang Jiang MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, ChinaSearch for more papers by this authorLi-Qun Wang, Corresponding Author Li-Qun Wang lqwang@zju.edu.cn MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China Li-Qun Wang, MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China. Hong-Cai Zhou, Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this authorHong-Cai Zhou, Corresponding Author Hong-Cai Zhou zhou@mail.chem.tamu.edu Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USA Li-Qun Wang, MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China. Hong-Cai Zhou, Department of Chemistry, Texas A&M University, College Station, Texas, 77842, USASearch for more papers by this author First published: 22 October 2010 https://doi.org/10.1002/adma.201003012Citations: 292Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Porous coordination nanocages covered with alkyne groups are synthesized through judicious selection of the ligand and reaction conditions. The surface functionalization via click reaction with azide-terminated polyethylene glycol turns them into water-stable colloids, which exhibit controlled release of an anticancer drug 5-fluorouracil. Citing Literature Supporting Information Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description adma_201003012_sm_suppl.pdf3.1 MB suppl Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume23, Issue1January 4, 2011Pages 90-93 RelatedInformation