Die Struktur einer Vitamin‐K 2 ‐Verbindung aus Tuberkelbazillen und die Synthese höherer Isoprenologe der Vitamin‐K 2 ‐Reihe
1960; Wiley; Volume: 43; Issue: 1 Linguagem: Inglês
10.1002/hlca.19600430155
ISSN1522-2675
AutoresHans Noll, R. Rüegg, Urs Gloor, G. Ryser, O. Isler,
Tópico(s)Chemistry and Chemical Engineering
ResumoAbstract Vitamin K 2(x) m.p. 58–59º, isolated by N OLL from M. tuberculosis , proved to be 2‐methyl‐3‐solanesyl‐1,4‐naphthoquinone having a side‐chain of 45 C‐atoms. This vitamin K 2(45) was synthesized from menadiol and solanesol. The next higher isoprenologue, vitamin K 2(50) m.p. p. 62°, was obtained by lengthening solanesol by an isoprene unit followed by condensation with menadiol and oxidation.
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