Light and Agonists Alter Pineal N -Acetyltransferase Induction by Vasoactive Intestinal Polypeptide
1983; American Association for the Advancement of Science; Volume: 220; Issue: 4601 Linguagem: Inglês
10.1126/science.6844931
ISSN1095-9203
Autores Tópico(s)Neuropeptides and Animal Physiology
ResumoVasoactive intestinal polypeptide stimulated serotonin N -acetyltransferase activity in rat pineal glands in organ culture by a postsynaptic action that was independent of the beta-receptor. The magnitude of stimulation could be altered by environmental lighting conditions and by prior exposure to the agonist. Such up- and down-regulation, well known for catecholaminergic stimulation of this system, is compatible with a possible control of the pineal by vasoactive intestinal polypeptide as well as by catecholamines.
Referência(s)