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Searching for the missing heritability of complex diseases

2010; Wiley; Volume: 32; Issue: 2 Linguagem: Inglês

10.1002/humu.21392

1098-1004

Kari Hemminki, Asta Försti, Richard S. Houlston, Justo Lorenzo Bermejo,

Genetic Associations and Epidemiology

Human MutationVolume 32, Issue 2 p. 259-262 Letter to the Editors Searching for the missing heritability of complex diseases† Kari Hemminki, Corresponding Author Kari Hemminki [email protected] Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany Center for Primary Health Care Research, University of Lund, Malmö, SwedenDivision of Molecular Genetic Epidemiology, German Cancer Research Center, DKFZ, INF 580, Heidelberg, 69120 GermanySearch for more papers by this authorAsta Försti, Asta Försti Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany Center for Primary Health Care Research, University of Lund, Malmö, SwedenSearch for more papers by this authorRichard Houlston, Richard Houlston Section of Cancer Genetics, Institute of Cancer Research, Sutton Surrey, United KingdomSearch for more papers by this authorJusto Lorenzo Bermejo, Justo Lorenzo Bermejo Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany Institute of Medical Biometry and Informatics (IMBI), University Hospital Heidelberg, GermanySearch for more papers by this author Kari Hemminki, Corresponding Author Kari Hemminki [email protected] Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany Center for Primary Health Care Research, University of Lund, Malmö, SwedenDivision of Molecular Genetic Epidemiology, German Cancer Research Center, DKFZ, INF 580, Heidelberg, 69120 GermanySearch for more papers by this authorAsta Försti, Asta Försti Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany Center for Primary Health Care Research, University of Lund, Malmö, SwedenSearch for more papers by this authorRichard Houlston, Richard Houlston Section of Cancer Genetics, Institute of Cancer Research, Sutton Surrey, United KingdomSearch for more papers by this authorJusto Lorenzo Bermejo, Justo Lorenzo Bermejo Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany Institute of Medical Biometry and Informatics (IMBI), University Hospital Heidelberg, GermanySearch for more papers by this author First published: 28 October 2010 https://doi.org/10.1002/humu.21392Citations: 10 † Communicated by Richard G.H. Cotton Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References Bodmer W, Bonilla C. 2008. Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet 40: 695– 701. Chung CC, Magalhaes WC, Gonzalez-Bosquet J, Chanock SJ. 2010. Genome-wide association studies in cancer—current and future directions. Carcinogenesis 31: 111– 120. Economou M, Trikalinos TA, Loizou KT, Tsianos EV, Ioannidis JP. 2004. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. 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