Insulin‐like growth factors and diabetes
1992; Wiley; Volume: 8; Issue: 3 Linguagem: Inglês
10.1002/dmr.5610080304
ISSN1099-0895
AutoresLeon A. Bach, Matthew M. Rechler,
Tópico(s)Metabolism, Diabetes, and Cancer
ResumoDiabetes/Metabolism ReviewsVolume 8, Issue 3 p. 229-257 Article Insulin-like growth factors and diabetes Dr Leon A. Bach, Corresponding Author Dr Leon A. Bach Growth and Development Section, Molecular and Nutritional Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, U.S.A.National Institutes of Health, Bldg 10, Rm 8D14, Bethesda, MD 20892, U.S.A.Search for more papers by this authorMatthew M. Rechler, Matthew M. Rechler Growth and Development Section, Molecular and Nutritional Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, U.S.A.Search for more papers by this author Dr Leon A. Bach, Corresponding Author Dr Leon A. Bach Growth and Development Section, Molecular and Nutritional Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, U.S.A.National Institutes of Health, Bldg 10, Rm 8D14, Bethesda, MD 20892, U.S.A.Search for more papers by this authorMatthew M. Rechler, Matthew M. Rechler Growth and Development Section, Molecular and Nutritional Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, U.S.A.Search for more papers by this author First published: October 1992 https://doi.org/10.1002/dmr.5610080304Citations: 71AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Baxter RC: The somatomedins: insulin-like growth factors. Adv Clin Chem 25: 49– 115, 1986. 2 Daughaday WH, and Rotwein P: Insulin-like growth factors I, and II. Peptide messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev 10: 68– 91, 1989. 3 Humbel RE: Insulin-like growth factors I, and II. Eur J Biochem 190: 445– 462, 1990. 4 Holthuizen E, LeRoith D, Lund PK, Roberts C, Rotwein P, Spencer EM, and Sussenbach JS: Revised nomenclature for the insulin-like growth factor genes and transcripts. In Modern Concepts of Insulin-like Growth Factors, EM Spencer, Ed. Elsevier, New York, 1992, pp. 733– 736. 5 Salmon WD, Jr., and Daughaday WH: A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro. J Lab Clin Med 49: 825– 836, 1957. 6 Behringer RR, Lewin TM, Quaife CJ, Palmiter RD, Brinster RL, and D'Ercole AJ: Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice. Endocrinology 127: 1033– 1040, 1990. 7 Schoenle E, Zapf J, Humbel ER, and Froesch ER: Insulin-like growth factor I stimulates growth in hypophysectomized rats. Nature 296: 252– 253, 1982. 8 Skottner A, Clark RG, Fryklund L, and Robinson ICAF: Growth responses in a mutant dwarf rat to human growth hormone and recombinant human insulin-like growth factor I. Endocrinology 124: 2519– 2526, 1989. 9 Robinson ICAF, and Clark RG: Growth promoting activity of IGF-1 in the rat. Acta Paediatr Scand (Suppl) 347: 93– 103, 1988. 10 Guler H-P, Zapf J, Scheiwiller E, and Froesch ER: Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats. Proc Natl Acad Sci USA 85: 4889– 4893, 1988. 11 D'Ercole AJ, Stiles AD, and Underwood LE: Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci USA 81: 935– 939, 1984. 12 Murphy LJ, Bell GI, and Friesen HG: Tissue distribution of insulin-like growth factor I, and II messenger ribonucleic acid in the adult rat. Endocrinology 120: 1279– 1282, 1987. 13 Lund PK, Moats-Staats BM, Hynes MA, Simmons JG, Jansen M, D'Ercole AJ, and Van Wyk JJ: Somatomedin-C/insulin-like growth factor-I, and insulin-like growth factor-II mRNAs in rat fetal and adult tissues. J Biol Chem 261: 14539– 14544, 1986. 14 D'Ercole AJ, and Underwood LE: Estimation of tissue concentrations of somatomedin C/insulin-like growth factor I. Methods Enzymol 146: 227– 233, 1988. 15 Macauley VM: Insulin-like growth factors and cancer. Br J Cancer 65: 311– 320, 1992. 16 Nakanishi Y, Mulshine JL, Kasprzyk PG, Natale RB, Maneckjee R, Avis I, Treston AM, Gazdar AF, Minna JD, and Cuttitta F: Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro. J Clin Invest 82: 354– 359, 1988. 17 Yee D, Paik S, Lebovic GS, Marcus RR, Favoni RE, Cullen KJ, Lippman ME, and Rosen N: Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer. Mol Endocrinol 3: 509– 517, 1989. 18 Guler H-P, Zapf J, and Froesch ER: Short-term metabolic effects of recombinant human insulinlike growth factor I in healthy adults. N Engl J Med 317: 137– 140, 1987. 19 Boulware SD, Tamborlane WV, Matthews LS, and Sherwin RS: Diverse effects of insulin-like growth factor I on glucose, lipid, and amino acid metabolism. Am. J. Physiol 262: E130– E133, 1992. 20 Jacob R, Barrett E, Plewe G, Fagin KD, and Sherwin RS: Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat. Comparison with insulin. J Clin Invest 83: 1717– 1723, 1989. 21 Froesch ER, Schmid C, Schwander J, and Zapf J: Actions of insulin-like growth factors. Annu Rev Physiol 47: 443– 467, 1985. 22 Bolinder J, Lindblad A, Engfeldt P, and Arner P: Studies of acute effects of insulin-like growth factors I, and II in human fat cells. J Clin Endocrinol Metab 65: 732– 737, 1987. 23 Poggi C, Le Marchand-Brustel Y, Zapf J, Froesch ER, and Freychet P: Effects and binding of insulin-like growth factor IGF-I in the isolated soleus muscle of lean and obese mice: comparison with insulin. Endocrinology 105: 723– 730, 1979. 24 Bilan PJ, Mitsumoto Y, Ramlal T, and Klip A: Acute and long-term effects of insulin-like growth factor I on glucose transporters in muscle cells. Translocation and biosynthesis. FEBS Lett 298: 285– 290, 1992. 25 Maher F, Clark S, and Harrison LC: Chronic stimulation of glucose transporter gene expression in L6 myocytes mediated via the insulin-like growth factor-1 receptor. Mol Endocrinol 3: 2128– 2135, 1989. 26 Weiland M, Schurmann A, Schmidt WE, and Joost HG: Development of the hormone-sensitive glucose transport activity in differentiating 373–11 murine fibroblasts. Role of the two transporter species and their subcellular localization. Biochem J 270: 331– 6, 1990. 27 Masters BA, Werner H, Roberts CT, Jr., LeRoith D, and Raizada MK: Developmental regulation of insulin-like growth factor-I-stimulated glucose transporter in rat brain astrocytes. Endocrinology 128: 2548– 2557, 1991. 28 Sandahl Christiansen J, Gammelgaard J, Orskov H, Andersen AR, Telmer S, and Parving HH: Kidney function and size in normal subjects before and during growth hormone administration for one week. Eur J Clin Invest 11: 487– 490, 1981. 29 Hirschberg R, and Kopple JD: Effects of growth hormone and IGF-I on renal function. Kidney Int 36: S20– S26, 1989. 30 Guler HP: Insulin-like growth factor I increases glomerular filtration rate and renal plasma flow in man. Acta Endocrinol 121: 101– 106, 1989. 31 Hirschberg R, and Kopple JD: Evidence that insulin-like growth factor I increases renal plasma flow and glomerular filtration rate in fasted rats. J Clin Invest 83: 326– 330, 1989. 32 Lowe WL, Adamo M, Werner H, Roberts CT, and LeRoith D: Regulation by fasting of rat insulin-like growth factor I, and its receptor. Effects on gene expression and binding. J Clin Invest 84: 619– 626, 1989. 33 Blazer-Yost BL, and Cox M: Insulin-like growth factor 1 stimulates renal epithelial Na+ transport. Am J Physiol 255: C413– C417, 1988. 34 Caverzasio J, and Bonjour JP: Influence of recombinant IGF-I (somatomedin C) on sodium-dependent phosphate transport in cultured renal epithelium. Prog Clin Biol Res 252: 385– 386, 1988. 35 Stiles CD, Capone GT, Scher CD, Antoniades HN, Van Wyk JJ, and Pledger WJ: Dual control of cell growth by somatomedins and platelet-derived growth factor. Proc Natl Acad Sci USA 76: 1279– 1283, 1979. 36 Aron DC: Insulin-like growth factor I, and erythropoiesis. BioFactors 3: 211– 216, 1992. 37 Caroni P, and Grandes P: Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors. J Cell Biol 110: 1307– 1317, 1990. 38 Bar RS: Vascular endothelium and diabetes mellitus. In Endothelial Cell Dysfunctions, N Simionescu, and M Simionescu, Eds. Plenum Press, New York, 1992, pp 363– 381. 39 Moran A, Brown DM, Kim Y, and Klein DJ: Effects of IGF-I, and glucose on protein and proteoglycan synthesis by human fetal mesangial cells in culture. Diabetes 40: 1346– 1354, 1991. 40 Mathews LS, Norstedt G, and Palmiter RD: Regulation of insulin-like growth factor I gene expression by growth hormone. Proc Natl Acad Sci USA 83: 9343– 9347, 1986. 41 Roberts CT, Jr., Lasky SR, Lowe WL, Jr., Seaman WT, and LeRoith D: Molecular cloning of rat insulin-like growth factor I complementary deoxyribonucleic acids: differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues. Mol Endocrinol 1: 243– 248, 1987. 42 Murphy LJ, Bell GI, Duckworth ML, and Friesen HG: Identification, characterization, and regulation of a rat complementary deoxyribonucleic acid which encodes insulin-like growth factor-I. Endocrinology 121: 684– 691, 1987. 43 Clemmons D: Use of insulin-like growth factor-I measurements in diagnosis and in monitoring therapy. In Insulin-like Growth Factors in Health and Disease, LeRoith D, Moderator. Ann Intern Med 116: 854– 862, 1992. 44 Hall K, Lundin G, and Povoa G: Serum levels of the low molecular weight form of insulin-like growth factor binding protein in healthy subjects and patients with growth hormone deficiency, acromegaly and anorexia nervosa. Acta Endocrinol 118: 321– 326, 1988. 45 Thissen JP, Triest S, Maes M, Underwood LE, and Ketelslegers JM: The decreased plasma concentration of insulin-like growth factor I in protein-restricted rats is not due to decreased numbers of growth hormone receptors on isolated hepatocytes. J Endocrinol 124: 159– 165, 1990. 46 Maiter D, Fliesen T, Underwood LE, Maes M, Gerard G, Davenport ML, and Ketelslegers JM: Dietary protein restriction decreases insulin-like growth factor I independent of insulin and liver growth hormone binding. Endocrinology 124: 2604– 2611, 1989. 47 Miller LL, Schalch DS, and Drazin B: Role of the liver in regulating somatomedin activity: effects of streptozotocin diabetes and starvation on the synthesis and release of insulin-like growth factor and its carrier protein by the isolated perfused rat liver. Endocrinology 108: 1265– 1271, 1981. 48 Bornfeldt KE, Arnqvist HJ, Enberg B, Mathews LS, and Norstedt G: Regulation of insulin-like growth factor I, and growth hormone receptor gene expression by diabetes and nutritional state in rat tissues. J Endocrinol 122: 651– 656, 1989. 49 Merimee TJ, Zapf J, and Froesch ER: Insulin-like growth factors in the fed and fasted state. J Clin Endocrinol Metab 55: 999– 1002, 1982. 50 Shapiro B, and Pimstone BL: Sulphation factor (somatomedin activity) in experimental protein malnutrition in the rat. J Endocrinol 77: 233– 240, 1978. 51 Isley WL, Underwood LE, and Clemmons DR: Dietary components that regulate serum somatomedin-C in humans. J Clin Invest 71: 175– 182, 1983. 52 Bourguignon JP: Linear growth as a function of age at onset of puberty and sex steroid dosage: therapeutic implications. Endocr Rev 9: 467– 488, 1988. 53 Parker MW, Johanson AJ, Rogol AD, Kaiser DL, and Blizzard RM: Effects of testosterone on somatomedin-C concentrations in prepubertal boys. J Clin Endocrinol Metab 58: 87– 90, 1984. 54 Cicognani A, Cacciari E, Tacconi M, Pascucci MG, Tonioli S, Pirazzoli P, and Balsamo A: Effect of gonadectomy on growth hormone, IGF-1 and sex steroids in children with complete and incomplete androgen insensitivity. Acta Endocrinol 121: 777– 783, 1989. 55 Handelsman DJ, Spaliviero JA, Scott CD, and Baxter RC: Hormonal regulation of the peripubertal surge of insulin-like growth factor-I in the rat. Endocrinology 120: 491– 496, 1987. 56 Boni-Schnetzler M, Schmid C, Meier PJ, and Froesch ER: Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. Am J Physiol 260: E846– E851, 1991. 57 Salamon EA, Luo J, and Murphy LJ: The effect of acute and chronic insulin administration on insulin-like growth factor I expression in the pituitary-intact and hypophysectomised rat. Diabetologia 32: 347– 353, 1989. 58 Perdue JF, LeBon TR, Kato J, Hampton B, and Fujita-Yamaguchi Y: Binding specificities and transducing function of the different molecular weight forms of insulin-like growth factor-II (IGF-II) on IGF-I receptors. Endocrinology 129: 3101– 3108, 1991. 59 Hampton B, Burgess WH, Marshak DR, Cullen KJ, and Perdue JF: Purification and characterization of an insulin-like growth factor II variant from human plasma. J Biol Chem 264: 19155– 19160, 1989. 60 Zumstein PP, Luthi C, and Humbel RE: Amino acid sequence of a variant pro-form of insuli-like growth factor II. Proc Natl Acad Sci USA 82: 3169– 3172, 1985. 61 Bell GI, Gerhard DS, Fong NM, Sanchez-Pescador R, and Rall LB: Isolation of the human insulinlike growth factor genes: insulin-like growth factor II, and insulin genes are contiguous. Proc Natl Acad Sci USA 82: 6450– 6454, 1985. 62 DeChiara TM, Efstratiadis A, and Robertson EJ: A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345: 78– 80, 1990. 63 Rechler MM: Insulin-like growth factor II: gene structure and expression into messenger RNA, and protein. In Insulin-Like Growth Factors: Molecular and Cellular Aspects, D LeRoith, Ed. CRC Press, Boca Raton, 1991, pp 87– 110. 64 Sinha MK, Buchanan C, Raineri-Maldonado C, Khazanie P, Atkinson S, Dimarchi R, and Caro JF: IGF-II receptors and IGF-II-stimulated glucose transport in human fat cells. Am J Physiol 258: E534– E542, 1990. 65 Florini JR, Magri KA, Ewton DZ, James PL, Grindstaff K, and Rotwein PS: "Spontaneous" differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II. J Biol Chem 266: 15917– 15923, 1991. 66 El-Badry OM, Romanus JA, Helman LJ, Cooper MJ, Rechler MM, and Israel MA: Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II. J Clin Invest 84: 829– 839, 1989. 67 El-Badry OM, Minniti C, Kohn EC, Houghton PJ, Daughaday WH, and Helman LJ: Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. Cell Growth & Differentiation 1: 325– 331, 1990. 68 Daughaday WH, Emanuele MA, Brooks MH, Barbato AL, Kapadia M, and Rotwein P: Synthesis and secretion of insulin-like growth factor II by a leiomyosarcoma with associated hypoglycemia. N Engl J Med 319: 1434– 1440, 1988. 69 Tseng LY-H, Brown AL, Yang YW-H, Romanus JA, Orlowski CC, Taylor T, and Rechler MM: The fetal rat binding protein for insulin-like growth factors is expressed in the choroid plexus and cerebrospinal fluid of adult rats. Mol Endocrinol 3: 1559– 1568, 1989. 70 Zapf J, Walter H, and Froesch ER: Radioimmunological determination of insulin-like growth factors I, and II in normal subjects and in patients with growth disorders and extrapancreatic tumor hypoglycemia. J Clin Invest 68: 1321– 1330, 1981. 71 Scott J, Cowell J, Robertson ME, Priestley LM, Wadey R, Hopkins B, Pritchard J, Bell GI, Rall LB, Graham CF, and Knott TJ: Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues. Nature 317: 260– 262, 1985. 72 Soos MA, Whittaker J, Lammers R, Ullrich A, and Siddle K: Receptors for insulin and insulinlike growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells. Biochem J 270: 383– 390, 1990. 73 Soos MA, and Siddle K: Immunological relationships between receptors for insulin and insulinlike growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors involving hybrids with insulin receptors. Biochem J 263: 553– 563, 1989. 74 Moxham CP, Duronio B, and Jacobs S: Insulinlike growth factor I receptor beta-subunit heterogeneity. Evidence for hybrid tetramers composed of insulin-like growth factor I, and insulin receptor heterodimers. J Biol Chem 264: 13238– 13244, 1989. 75 Nissley P, and Lopaczynski W: Insulin-like growth factor receptors. Growth Factors 5: 29– 43, 1991. 76 Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA, Cahill DA, Goldstein BJ, and White MF: Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 352: 73– 77, 1991. 77 Yamamoto K, Lapetina EG, and Moxham CP: Insulin-like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor. Endocrinology 130: 1490– 1498, 1992. 78 Yamamoto K, Altschuler D, Wood E, Horlick K, Jacobs S, and Lapetina EG: Association of phosphorylated insulin-like growth factor-I receptor with the SH2 domains of phosphatidylinositol 3-kinase p85. J Biol Chem 267: 11337– 11343, 1992. 79 Weiland M, Bahr F, Höhne M, Schürmann A, Ziehm D, and Joost HG: The signalling potential of the receptors for insulin and insulin-like growth factor I (IGF-I) in 3T3-L1 adipocytes: comparison of glucose transport activity, induction of oncogene c-fos, glucose transporter mRNA, and DNA-synthesis. J Cell Physiol 149: 428– 435, 1991. 80 Ong J, Yamashita S, and Melmed S: Insulinlike growth factor I induces c-fos messenger ribonucleic acid in L6 skeletal muscle cells. Endocrinology 120: 353– 357, 1987. 81 Oemar BS, Law NM, and Rosenzweig SA: Insulinlike growth factor-1 induces tyrosyl phosphorylation of nuclear proteins. J Biol Chem 266: 24241– 24244, 1991. 82 Guse AH, Kiess W, Funk B, Kessler U, Berg I, and Gercken G: Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. Endocrinology 130: 145– 151, 1992. 83 Lu K, and Campisi J: Ras proteins are essential and selective for the action of insulin-like growth factor 1 late in the G1 phase of the cell cycle in BALB/c murine fibroblasts. Proc Natl Acad Sci USA 89: 3889– 3893, 1992. 84 Morgan DO, Edman JC, Standring DN, Fried VA, Smith MC, Roth RA, and Rutter WJ: Insulin-like growth factor II receptor as a multifunctional binding protein. Nature 329: 301– 307, 1987. 85 Kiess W, Blickenstaff GD, Sklar MM, Thomas CL, Nissley SP, and Sahagian GG: Biochemical evidence that the type II insulin-like growth factor receptor is identical to the cation-independent mannose 6-phosphate receptor. J Biol Chem 263: 9339– 9344, 1988. 86 Braulke T, Causin C, Waheed A, Junghans U, Hasilik A, Maly P, Humbel RE, and von Figura K: Mannose 6-phosphate/insulin-like growth factor II receptor: distinct binding sites for mannose 6-phosphate and insulin-like growth factor II. Biochem Biophys Res Commun 150: 1287– 1293, 1988. 87 Waheed A, Braulke T, Junghans U, and von Figura K: Mannose 6-phosphate/insulin-like growth factor II receptor: the two types of ligands bind simultaneously to one receptor at different sites. Biochem Biophys Res Commun 152: 1248– 1254, 1988. 88 MacDonald RG, Tepper MA, Clairmont KB, Perregaux SB, and Czech MP: Serum form of the rat insulin-like growth factor II/mannose 6-phosphate receptor is truncated in the carboxyl-terminal domain. J Biol Chem 264: 3256– 3261, 1989. 89 Rechler MM, and Nissley SP: The nature and regulation of the receptors for insulin-like growth factors. Annu Rev Physiol 47: 425– 442, 1985. 90 Rogers SA, and Hammerman MR: Insulin-like growth factor II stimulates production of inositol trisphosphate in proximal tubular basolateral membranes from dog kidney. Proc Natl Acad Sci USA 85: 4037– 4041, 1988. 91 Hammerman MR, and Gavin JR, III: Binding of insulin-like growth factor II, and multiplication-stimulating activity-stimulated phosphorylation in basolateral membranes from dog kidney. J Biol Chem 259: 13511– 13517, 1984. 92 Bhaumick B, and Bala RM: Parallel effects of insulin-like growth factor-II, and insulin on glucose metabolism of developing mouse embryonic limb buds in culture. Biochem Biophys Res Commun 152: 359– 367, 1988. 93 Hartshorn MA, Scott CD, and Baxter RC: Immunofluorescent localization of type II insulin-like growth factor receptor in rat liver and hepatoma cells. J Endocrinol 121: 221– 227, 1989. 94 Polychronakos C, Guyda HJ, and Posner BI: Increase in the type 2 insulin-like growth factor receptors in the rat kidney during compensatory growth. Biochem Biophys Res Commun 132: 418– 423, 1985. 95 Kiess W, Thomas CL, Sklar MM, and Nissley SP: β-Galactosidase decreases the binding affinity of the insulin-like growth factor-II/mannose-6-phosphate receptor for insulin-like growth factor II. Eur J Biochem 190: 71– 77, 1990. 96 Nishimoto I, Murayama Y, Katada T, Ui M, and Ogata E: Possible direct linkage of insulin-like growth factor-II receptor with guanine nucleotide-binding proteins. J Biol Chem 264: 14029– 14038, 1989. 97 Okamoto T, Asano T, Harada S, Ogata E, and Nishimoto I: Regulation of transmembrane signal transduction of insulin-like growth factor II by competence type growth factors or viral ras p21. J Biol Chem 266: 1085– 1091, 1991. 98 Campbell PG, Novak JF, Yanosick TB, and McMaster JH: Involvement of the plasmin system in dissociation of the insulin-like growth factor-binding protein complex. Endocrinology 130: 1401– 1412, 1992. 99 Povoa G, Enberg G, Jornvall H, and Hall K: Isolation and characterization of a somatomedin-binding protein from mid-term human amniotic fluid. Eur J Biochem 144: 199– 204, 1984. 100 Clemmons DR: The role of insulin-like growth factor binding proteins in controlling the expression of IGF actions. In Molecular and Cellular Biology of Insulin-like Growth Factors and their Receptors, D LeRoith, and MK Raizada, Eds. Plenum Press, New York, 1989, pp 381– 394. 101 Jones JI, D'Ercole AJ, Camacho-Hubner C, and Clemmons DR: Phosphorylation of insulin-like growth factor (IGF)-binding protein in cell culture and in vivo: effects on affinity for IGF-1. Proc Natl Acad Sci USA 88: 7481– 7485, 1991. 102 Frost RA, and Tseng L: Insulin-like growth factor binding protein-1 is phosphorylated by cultured human endometrial stromal cells and multiple protein kinases in vitro. J Biol Chem 266: 18082– 18088, 1991. 103 Elgin GR, Busby WH, Jr., and Clemmons DR: An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I. Proc Natl Acad Sci USA 84: 3254– 3258, 1987. 104 Clemmons DR, Cascieri MA, Camacho-Hubner C, McCusker RH, and Bayne ML: Discrete alterations of the insulin-like growth factor I molecule which alter its affinity for insulin-like growth factor-binding proteins result in changes in bioactivity. J Biol Chem 265: 12210– 12216, 1990. 105 Drop SLS, Valiquette G, Guyda HJ, Corvol MT, and Posner BI: Partial purification and characterization of a binding protein for insulinlike activity (ILAs) in human amniotic fluid: a possible inhibitor of insulin-like activity. Acta Endocrinol (Copenhagen) 90: 505– 518, 1979. 106 Ritvos O, Ranta T, Jalkanen J, Suikkari A-M, Voutilainen R, Bohn H, and Rutanen EM: Insulin-like growth factor (IGF) binding protein from human decidua inhibits the binding and biological action of IGF-I in cultured choriocarcinoma cells. Endocrinology 122: 2150– 2157, 1988. 107 Ooi GT, Orlowski CC, Brown AL, Becker RE, Unterman TG, and Rechler MM: Different tissue distribution and hormonal regulation of mRNAs encoding rat insulin-like growth factor binding proteins rIGFBP-1 and rIGFBP-2. Mol Endocrinol 4: 321– 328, 1990. 108 Baxter RC, and Cowell CT: Diurnal rhythm of growth hormone-independent binding protein for insulin-like growth factors in human plasma. J Clin Endocrinol Metab 65: 432– 440, 1987. 109 Villafuerte BC, Goldstein S, Murphy LJ, and Phillips LS: Nutrition and somatomedin. XXV. Regulation of insulin-like growth factor binding protein 1 in primary cultures of normal rat hepatocytes. Diabetes 40: 837– 841, 1991. 110 Conover CA, and Lee PDK: Insulin regulation of insulin-like growth factor-binding protein production in cultured HepG2 cells. J Clin Endocrinol Metab 70: 1062– 1067, 1990. 111 Lewitt MS, and Baxter RC: Regulation of growth hormone-independent insulin-like growth factor-binding protein (BP-28) in cultured human fetal liver explants. J Clin Endocrinol Metab 69: 246– 252, 1989. 112 Orlowski CC, Ooi GT, Brown DR, Yang YW-H, Tseng LY-H, and Rechler MM: Insulin rapidly inhibits insulin-like growth factor binding protein-1 gene expression in H4-II-E rat hepatoma cells. Mol Endocrinol 5: 1180– 1187, 1991. 113 Powell DR, Suwanichkul A, Cubbage ML, DePaolis LA, Snuggs MB, and Lee PDK: Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1. J Biol Chem 266: 18868– 18876, 1991. 114 Bar RS, Boes M, Clemmons DR, Busby WH, Sandra A, Dake BL, and Booth BA: Insulin differentially alters transcapillary movement of intravascular IGFBP-1, IGFBP-2 and endothelial cell IGF-binding proteins in the rat heart. Endocrinology 127: 497– 499, 1990. 115 Yeoh SI, and Baxter RC: Metabolic regulation of the growth hormone independent insulin-like growth factor binding protein in human plasma. Acta Endocrinol (Copenhagen) 119: 465– 473, 1988. 116 Busby WH, Snyder DK, and Clemmons DR: Radioimmunoassay of a 26,000-dalton plasma insulin-like growth factor-binding protein: control by nutritional variables. J Clin Endocrinol Metab 67: 1225– 1230, 1988. 117 Brismar K, Gutniak M, Povoa G, Werner S, and Hall K: Insulin regulates the 35 kDa IGF binding protein in patients with diabetes mellitus. J Endocrinol Invest 11: 599– 602, 1988. 118 Suikkari A-M, Sane T, Seppälä M, Hannele Y-J, Karonen S-L, and Koivisto VA: Prolonged exercise increases serum insulin-like growth factor-binding protein concentrations. J Clin Endocrinol Metab 68: 141– 144, 1989. 119 Suikkari AM, Koivisto VA, Rutanen EM, Yki-Jarvinen H, Karonen SL, and Seppälä M: Insulin regulates the serum levels of low molecular weight insulin-like growth factor-binding protein. J Clin Endocrinol Metab 66: 266– 272, 1988. 120 Suikkari A-M, Koivisto VA, Koistinen R, Seppälä M, and Yki-Jarvinen H: Dose-response characteristics for suppression of low molecular weight plasma insulin-like growth factor-binding protein by insulin. J Clin Endocrinol Metab 68: 135– 140, 1989. 121 Snyder DK, and Clemmons DR: Insulin dependent regulation of IGFBP-1. J Clin Endocrinol Metab 71: 1632– 1636, 1990. 122 Lewitt MS, Denyer GS, Cooney GJ, and Baxter RC: Insulin-like growth factor-binding protein-1 modulates blood glucose levels. Endocrinology 129: 2254– 2256, 1991. 123 Lewitt MS, and Baxter RC: Insulin-like growth factor-binding protein-1: a role in glucose counterregulation? Mol Cell Endocrinol 79: C147– C152, 1991. 124 Seneviratne C, Jiangming L, and Murphy LJ: Transcriptional regulation of rat insulin-like growth factor-binding protein-1 expression by growth hormone. Mol Endocrinol 4: 1199– 1204, 1990. 125 Luo JM, Reid RE, and Murphy LJ: Dexa
Referência(s)