Artigo Revisado por pares

An efficient strategy for the synthesis of polysubstituted chromeno[4,3-b]pyrrolidine derivatives

2014; Royal Society of Chemistry; Volume: 50; Issue: 19 Linguagem: Inglês

10.1039/c3cc49504c

ISSN

1364-548X

Autores

Li Tian, Guo‐Qiang Xu, Yun‐Han Li, Yong‐Min Liang, Peng‐Fei Xu,

Tópico(s)

Multicomponent Synthesis of Heterocycles

Resumo

A powerful cascade reaction was developed for the synthesis of chromeno[4,3-b]pyrrolidines with high yields and excellent stereoselectivities. This efficient cascade reaction expeditiously established two fused rings which bear three contiguous stereogenic centers including one quaternary stereocenter in a single operation with low catalyst loading under mild conditions.

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