Anti‐Lu8, an Antibody Recognizing Another Lutheran‐Related Antigen
1972; Wiley; Volume: 23; Issue: 5 Linguagem: Inglês
10.1111/j.1423-0410.1972.tb03835.x
ISSN1423-0410
AutoresMija MacIlroy, J. McCreary, Marjory Stroup,
Tópico(s)Monoclonal and Polyclonal Antibodies Research
ResumoAbstract. An antibody defining another high‐frequency antigen within the Lutheran system, designated as anti‐Lu8, has been found in the serum of a Caucasian woman. The serum is compatible with Lu(a‐b‐) cells of the dominant and recessive types but reacts with Lu(a‐b+) cells that are Lu(‐4), Lu(‐5), Lu(‐6) and Lu(‐7). All of the family members are Lu(a‐b+). The red cells of two of the four siblings are not agglutinated by the serum but the red cells of her parents and two children are agglutinated suggesting that Lu8 is controlled by an autosomal dominant gene.
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