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Population data and sequence analysis of a ‘new’ microsatellite locus HumHUU (D16S3433)

2010; Elsevier BV; Volume: 4; Issue: 5 Linguagem: Inglês

10.1016/j.fsigen.2010.03.018

1878-0326

Magdalena Konarzewska, Witold Pepiński, Agata Jagiełło, Magdalena Spólnicka, Ireneusz Sołtyszewski, Andrzej Płucienniczak, Jarosław Berent,

Genetic Mapping and Diversity in Plants and Animals

This study reports sequence characteristics and population genetic data on a 'new' STR locus HumHUU (D16S3433) located in the non-coding region of chromosome 16q. Based on a population sample of 306 non-related Polish individuals 205 genotypes and 15 alleles with length range of 157-211bp were distinguished. No deviation from HWE was observed. The sequence analysis of each D16S3433 allele revealed a tetranucleotide repeat motif with a basic sequence structure (AAAA)(0-1)(AAAG)(11-22)(AAAAG)(AAAA)(AG)(AAAAAAG). The power of discrimination is 0.9538, showing a high degree of polymorphism. The presented results demonstrate that the D16S3433 is a useful genetic marker for forensic purposes and paternity testing.