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Efficacy of antibiotic-impregnated external ventricular drain catheters

2010; Elsevier BV; Volume: 17; Issue: 3 Linguagem: Inglês

10.1016/j.jocn.2009.06.016

1532-2653

Sharmini Muttaiyah, Stephen Ritchie, Sayona John, Edward Mee, Sally Roberts,

Neurosurgical Procedures and Complications

We prospectively compared the incidence of ventriculitis associated with external ventricular drains (EVD) impregnated with clindamycin and rifampicin with historical controls. We found the use of antibiotic impregnated (AI) EVDs showed a significant decrease in positive cerebrospinal fluid cultures and a significant delay in time to EVD infection.