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Ocular Axial Length and Its Associations in an Adult Population of Central Rural India: The Central India Eye and Medical Study

2010; Elsevier BV; Volume: 117; Issue: 7 Linguagem: Inglês

10.1016/j.ophtha.2009.11.040

1549-4713

Vinay Nangia, Jost B. Jonas, Ajit Sinha, Arshia Matin, Maithili Kulkarni, Songhomitra Panda‐Jonas,

Glaucoma and retinal disorders

Purpose To investigate the normal distribution of axial length of the globe, which is a major measurement of the eye, and its associations with other ocular and systemic parameters. Design Population-based study. Participants The Central India Eye and Medical Study is a population-based study performed in a rural region of central India. The study comprised 4711 subjects (aged 30+ years) of 5885 eligible individuals (response rate, 80.1%). Methods A detailed ophthalmic and medical examination was performed. The axial length was measured sonographically. Main Outcome Measures Axial length. Results Axial length measurements were available on 4698 study participants (99.7%). Their mean age was 49.4±13.4 years (range, 30–100 years), and the mean refractive error was −0.18±1.48 diopters (range, −20.0 to +7.25 diopters). Mean axial length was 22.6±0.91 mm (range, 18.22–34.20 mm). In multivariate analysis, axial length was significantly (P 0.15) in univariate or multivariate analysis. Conclusions In a rural population of central India, the mean ocular axial length was 22.6±0.91 mm, which was shorter than that of other populations. Axial length was associated with the systemic parameters of increased age, taller body height, greater body mass index, and a higher level of education, and with the ocular parameters of lower best-corrected visual acuity, lower corneal refractive power, deeper anterior chamber, thicker lens, and more myopic spherical and cylindrical refractive power. These associations were valid only for those eyes that were not highly myopic, whereas axial length was associated with refractive error only in highly myopic eyes. Financial Disclosure(s) Proprietary or commercial disclosure may be found after the references. To investigate the normal distribution of axial length of the globe, which is a major measurement of the eye, and its associations with other ocular and systemic parameters. Population-based study. The Central India Eye and Medical Study is a population-based study performed in a rural region of central India. The study comprised 4711 subjects (aged 30+ years) of 5885 eligible individuals (response rate, 80.1%). A detailed ophthalmic and medical examination was performed. The axial length was measured sonographically. Axial length. Axial length measurements were available on 4698 study participants (99.7%). Their mean age was 49.4±13.4 years (range, 30–100 years), and the mean refractive error was −0.18±1.48 diopters (range, −20.0 to +7.25 diopters). Mean axial length was 22.6±0.91 mm (range, 18.22–34.20 mm). In multivariate analysis, axial length was significantly (P 0.15) in univariate or multivariate analysis. In a rural population of central India, the mean ocular axial length was 22.6±0.91 mm, which was shorter than that of other populations. Axial length was associated with the systemic parameters of increased age, taller body height, greater body mass index, and a higher level of education, and with the ocular parameters of lower best-corrected visual acuity, lower corneal refractive power, deeper anterior chamber, thicker lens, and more myopic spherical and cylindrical refractive power. These associations were valid only for those eyes that were not highly myopic, whereas axial length was associated with refractive error only in highly myopic eyes.