Produção Nacional
Revisado por pares
Alicata disease: neuroinfestation by Angiostrongylus cantonensis in Recife, Pernambuco, Brazil
2009; Thieme Medical Publishers (Germany); Volume: 67; Issue: 4 Linguagem: Inglês
10.1590/s0004-282x2009000600025
ISSN1678-4227
AutoresAna Rosa Melo Corrêa Lima, Solange Dornelas Mesquita, Silvana Sobreira Santos, Eduardo Raniere Pessoa de Aquino, Luana da Rosa, Fábio Souza Duarte, Alessandra Oliveira Teixeira, Zenize Rocha da Silva Costa, Maria Lúcia Brito Ferreira,
Tópico(s)Parasitic infections in humans and animals
ResumoAngiostrongylus cantonensis, is a nematode in the Secernentea class, Strongylidae order, Metastrongylidae superfamily and Angiostrongylidae family 1 , and is the most common cause of human eosinophilic meningitis worldwide.This parasite has rats and other mammals as definitive hosts and snails, freshwater shrimp, fish, frogs and monitor lizards as intermediate hosts 1 .Mammals are infected by ingestion of intermediate hosts and raw/undercooked snails or vegetables, containing third-stage larvae 2 .Once infested, the larvae penetrate the vasculature of the intestinal tract and promote an inflammatory reaction with eosinophilia and lymphocytosis.This produces rupture of the bloodbrain barrier, changes to nervous tissue and damage to the Purkinje cells in the cerebellum, thereby promoting eosinophilic meningoencephalitis or Alicata disease 3 .A. cantonensis has been found in Southeast Asia and the South Pacific, where it is endemic 2 , as well as in Africa, India, Caribbean, Australia, North America, Jamaica, Haiti, Cuba, Puerto Rico 3 and Brazil 4 .cASE
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