Multifunctional compartments in the nucleus: Insights from DNA and RNA localization
1996; Wiley; Volume: 62; Issue: 2 Linguagem: Inglês
10.1002/(sici)1097-4644(199608)62
ISSN1097-4644
AutoresChristine Clemson, Jeanne B. Lawrence,
Tópico(s)Plant Molecular Biology Research
ResumoJournal of Cellular BiochemistryVolume 62, Issue 2 p. 181-190 Prospects Multifunctional compartments in the nucleus: Insights from DNA and RNA localization Christine Moulton Clemson, Christine Moulton Clemson Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655Search for more papers by this authorJeanne Bentley Lawrence, Corresponding Author Jeanne Bentley Lawrence Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655.Search for more papers by this author Christine Moulton Clemson, Christine Moulton Clemson Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655Search for more papers by this authorJeanne Bentley Lawrence, Corresponding Author Jeanne Bentley Lawrence Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655.Search for more papers by this author First published: August 1996 https://doi.org/10.1002/(SICI)1097-4644(199608)62:2 3.0.CO;2-OCitations: 32AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References Berezney R and DS Coffey (1974): Identification of a nuclear protein matrix. Biochem Biophys Res Commun 60: 1410– 1417. Bernhard W (1969): A new staining procedure for electron microscopical cytology. J Ultrastruct Res 27: 250– 265. Blencowe BJ, Nickerson JA, Issner R, Penman S, Sharp PA (1994): Association of nuclear matrix antigens with exon-containing splicing complexes. J Cell Biol 127: 593– 607. Brasch K (1990): Drug and metabolite-induced perturbations in nuclear structure and function: a review. Biochem. Cell. Biol. 68: 408– 426. Bregman DB, Du L, van der Zee S, Warren SL (1995): Transcription-dependent redistribution of the large sub-unit of RNA polymerase II to discrete nuclear domains. J Cell Biol 129(2): 287– 298. Brockdorff N, Ashworth A, Kay GF, McCabe VM, Norris DP, Cooper PJ, Swift S, Rastan S (1992): The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell 71: 515– 526. Brown CJ, Ballabio A, Rupert JL, Lafreniere RG, Grompe M, Tonlorenzi R, Willard HF (1991): A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature (Lond.) 349: 38– 44. Brown CJ, Hendrich BD, Rupert JL, Lafreniere RG, Xing Y, Lawrence JB, Willard HF (1992): The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell 71: 527– 542. Carter KC, Taneja KL, Lawrence JB (1991): Discrete nuclear domains of poly(A) RNA and their relationship to the functional organization of the nucleus. J Cell Biol 115: 1191– 1202. Carter KC, Bowman D, Carrington W, Fogarty K, McNeil JA, Fay FS, Lawrence JB (1993): A three-dimension view of precursor messenger RNA metabolism within the mammalian nucleus. Science (Wash. DC) 259: 1330– 1335. Clemson CM, McNeill JA, Willard HF, Lawrence JB (1996): XIST RNA paints the inactive X chromosome at interphase: evidence for a structural association. J Cell Biol 132: 259– 275. Cremer T, Kurz A, Zirbel R, Dietzel S, Rinke B, Schrock E, Speicher MR, Mathieu U, Jauch A, Emmerich P, Scherthan H, Reid T, Cremer C, Lichter P (1993): Role of Chromosome territories in the functional compartmentalization of the cell nucleus. Cold Spring Harbor Symp Quant Biol LVIII: 777– 792. Davis L, Cadrin M, Brown DL, Chaly N (1993): Reversible disassembly of transcription domains in lymphocyte nuclei during inhibition of RNA synthesis by DRB. Biol Cell 78: 163– 180. de Jong L, van Driel R, Stuurman N, Meijne AML, van Renswoude J (1990): Principles of nuclear organization. Cell Biol Int Rep 14: 1051– 1074. Dundr M, Raska I (1993): Non-isotopic ultrastructure mapping of transcription sites within the nucleus. Exp Cell Res 208:275. Fakan S (1994): Perichromatin fibrils are in situ forms of nascent transcripts. Trends Cell Biol 4: 86– 90. Fakan S, Puvion E (1980): The ultrastructural visualization of nuclear and extranucleolar RNA synthesis and distribution. Int Rev Cytol 65: 255– 299. Fakan S, Bernhard W (1971): Localization of rapidly and slowly labeled nuclear RNA as visualized by high resolution autoradiography. Exp Cell Res 67: 129– 141. Fey EG, Krochmalnic G, Penman S (1986): The nonchromatin substructures of the nucleus: the ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy. J Cell Biol 102: 1654– 1665. Frey MR, Matera AG (1995): Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells. Proc Natl Acad Sci USA 92: 5915– 5919. Fu X-D, Maniatis T (1990): Factor required for mammalian splicesome assembly is localized to discrete regions in the nucleus. Nature (Lond) 343: 437– 444. Gall JG, Stephenson EC, Erba HP, Diaz MO, Barsacchi-Pilone G (1981): Histone genes are located at the sphere loci of newt lampbrush chromosomes. Chromosoma 84: 159– 171. Harpold MM, Wilson MC, Darnell JE, Jr. (1981): Chinese hamster polyadenylated messenger ribonucleic acid: relationship to non-polyadenylated sequences and relative conservation during messenger ribonucleic acid processing. Mol Cell Biol 1(2): 188– 198. Hendzel MJ, Basett-Jones DP (1995): RNA polymerase II transcription and the functional organization of the mammalian cell nucleus. Chromosoma 103: 509– 516. Herman R, Weymouth L, Penman S (1978): Heterogeneous nuclear RNA-protein fibers in chromatin-depleted nuclei. J Cell Biol 78: 663– 674. Hogan NC, Traverse KL, Sullivan DE, Pardue M-L (1994): The nucleus-limited Hsr-Omega-n transcript is a polyadenylated RNA with a regulated intranuclear turnover. J Cell Biol 125(1): 21– 30. Huang S, Spector D (1991): Nascent pre-mRNA transcripts are associated with nuclear regions enriched in splicing factors. Genes & Dev 5: 2288– 2302. Huang S, Derrinck TJ, Ellisman MH, Spector DL (1994): In vivo analysis of the stability and transport of nuclear poly(A)+ RNA. J Cell Biol 126: 877– 899. Jackson DA, Hassan AB, Errington RJ, Cook PR (1993): Visualization of focal sites of transcription within human nuclei. EMBO (Eur Mol Biol Organ) J 12: 1059– 1065. Kay GF, Penny GD, Patel D, Ashworth A, Brockdorff N, Rastan S (1993): Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation. Cell 72: 171– 182. Kay GF, Barton SC, Surani MA, Rastan S (1994): Imprinting and X chromosome counting mechanisms determine Xist expression in early mouse development. Cell 77: 639– 650. Landegent JE, Jansen in de Wal N, Dirks RH, Bass F, Van der Ploeg M (1987): Use of whole cosmid genomic sequences for chromosomal location by non-radioactive in situ hybridization. Hum Genet 77:366. Langer-Safer PR, Levine M, Ward DC (1982): Immunological method for mapping genes on Drosophila polytene chromosomes. Proc Natl Acad Sci 79:4381. Lawrence JB, Vilnave CA, Singer RH (1988): Interphase chromatin and chromosome gene mapping by fluorescence detection of in situ hybridization reveals the presence and orientation of two closely integrated copies of EBV in human lymphoblastoid cell line. Cell 52: 51– 61. Lawrence JB, Singer RH, Marselle LM (1989): Highly localized distribution of specific transcripts within interphase nuclei visualized by in situ hybridization. Cell 57: 493– 502. Lawrence JB, Carter KC, Xing Y (1993): Probing functional organization within the nucleus: Is genome structure integrated with RNA metabolism? Cold Spring Harbor Symp Quant Biol 58: 807– 818. Lerner EA, Lerner MR, Janeway LA, Steitz JA (1981): Monoclonal antibodies to nucleic acid containing cellular constituents: probes for molecular biology and autoimmune disease. Proc Natl Acad Sci USA 78: 2737– 2741. Lewin B (1990): Genes IV. Oxford University Press, Oxford, England. 613 pp. Manning JE, Hershey ND, Broker TR, Pellegrini M, Mitchell HK, Davidson N (1975): A new method of in situ hybridization. Chromosoma 53:107. McCarrey JR, Dilworth DD (1992): Expression of Xist in mouse germ cells correlates with X-chromosome inactivation. Nature Gen 2: 200– 203. Migeon BR, Luo S, Jani M, Jeppesen P (1994): The severe phenotype of females with tiny ring X chromosomes is associated with inability of these chromosomes to undergo X inactivation. Am J Hum Genet 55: 497– 504. Moen Jr., PT, Smith KP, Lawrence JB (1995a): Compartmentalization of specific pre-mRNA metabolism: an emerging view. Human Molec Genet 4: 1779– 1789. Moen PT, Johnson CV, Wydner KL, Clemson CM, Coleman JR, Lawrence JB (1995b): Spatial relationship of intron-containing pre-mRNAs to SC-35 domains is gene specific. Molecular Biology of the Cell 6(Suppl): 305a. Nickerson JA, Krochmalnic G, Wan KM, Penman S (1989): Chromatin architecture and nuclear RNA. Proc Natl Acad Sci USA 86: 177– 181. Nickerson JA, Blencowe BJ, Penman S (1995): The architectural organization of nuclear metabolism. International Review of Cytology 162A: 67– 123. Nyman U, Hallan H, Hadlaczky G, Petterson I, Sharp G, Ringertz NR (1986): Intranuclear localization of snRNP antigens. J Cell Biol 102: 137– 143. O'Keefe RT, Mayeda A, Sadowski CL, Krainer AR, Spector DL (1994): Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors. J Cell Biol 124: 249– 260. Penny GD, Kay GF, Sheardown SA, Rastan S, Brockdorff N (1996): Requirement for Xist in X chromosome inactivation. Nature 379: 131– 137. Raska I, Andrade LEC, Ochs RL, Chan EKL, Chang C, Roos G, Tan EM (1991): Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies. Exp Cell Res 195: 27– 37. Richler C, Soreq H, Wahman J (1992): X inactivation in mammalian testis is correlated with inactive X specific transcription. Nat Genet 2: 192– 195. Salditt-Georgieff M, Harpold MM, Wilson MC, Darnell Jr., JE (1981): Large heterogeneous nuclear ribonucleic acid has three times as many 5′ caps as polyadenylic acid segments, and most caps do not enter polyribosomes. Mol Cell Biol 1(2): 179– 187. Salido EC, Yen PH, Thuluvancheri KM, Shapiro LJ (1992): Expression of the X-inactivation associated gene XIST during spermatogenesis. Nat Genet 2: 196– 199. Smith KP, Carter KC, Johnson CV, Lawrence JB (1995): U2 and U1 snRNA gene loci associate with coiled bodies. J Cell Biochem 59: 473– 485. Spector DL, Schrier WH, Busch H (1983): Immunoelectron microscopic localization of SnRNPS. Biol Cell 49: 1– 10. Spector DL (1990): Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles. Proc Natl Acad Sci USA 87: 147– 152. Spector DL, Fu X-D, Maniatis T (1991): Associations between distinct pre-mRNA splicing components and the cell nucleus. EMBO J 10:3467. Spector DL (1993): Macromolecular domains within the cell nucleus. Annu Rev Cell Biol 9: 265– 315. Stein GS, van Wijnen AJ, Stein JL, Lian JB, Bidwell JP, Montecino M (1994): Nuclear architecture supports integration of physiological regulatory signals for transcription of cell growth and tissue-specific genes during osteoblast differentiation. J Cell Biochem 55: 4– 15. Visa N Puvion-Dutilleul F, Harper F, Bachellerie J-P, Puvion E (1993): Intranuclear distribution of poly(A) RNA determined by electron microscope in situ hybridization. Exp Cell Res 208: 19– 34. Wang J Cao LG, Wang YL, Pederson T (1991): Localization of pre-messenger RNA at discrete nuclear sites. Proc Natl Acad Sci USA 88: 7391– 7395. Wansink DG, Schul W, van der Kraan I, van Steensel B, van Driel R, de Jong L (1993): Fluorescent labeling of nascent RNA reveals transcription by RNA polymerase II in domains scattered throughout the nucleus. J Cell Biol 122: 283– 293. Wolff DJ, Brown CJ, Schwartz S, Duncan AMV, Surti U, Willard HF (1994): Small marker X chromosomes lack the X inactivation center: Implications for karyotype/phenotype correlations. Am J Hum Genet 55: 87– 95. Xing Y (1993): Nuclear structure studied by fluorescence hybridization: visualization of individual gene transcription and RNA splicing. PhD Thesis. University of Massachusetts Medical Center, Worcester, MA. 125 pp. Xing Y, Lawrence JB (1993): Nuclear RNA tracks: structural basis for transcription and splicing? Trends Cell Biol 3: 346– 353. Xing Y, Johnson CV, Dobner P, Lawrence JB (1993): Higher level organization of individual gene transcription and RNA splicing: integration of nuclear structure and function. Science (Wash DC). 259: 1326– 1330. Xing Y, Johnson CV, Moen P, McNeil JA, Lawrence JB (1995): Non-random gene organization: structural arrangements of specific pre-mRNA transcription and splicing with SC-35 domains. J Cell Biol 131: 1635– 1647. Zamore PD, Green MR (1991): Biochemical characterization of U2 snRNP auxiliary factor: An essential pre-mRNA splicing factor with a novel intranuclear distribution. EMBO J 10: 207– 214. Zhang C, Taneja KL, Singer RH, Green MR (1994): Localization of pre-mRNA splicing in mammalian nuclei. Nature 372: 809– 812. Citing Literature Volume62, Issue2August 1996Pages 181-190 ReferencesRelatedInformation
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