Successful use of cisplatin to treat metastatic seminoma during cisplatin-induced acute renal failure
1991; Wiley; Volume: 68; Issue: 8 Linguagem: Inglês
10.1002/1097-0142(19911015)68
ISSN1097-0142
AutoresJ. G. Fox, Rachel Kerr, M. Soukop, John G. Farmer, Marjorie E. M. Allison,
Tópico(s)Testicular diseases and treatments
ResumoA chemotherapeutic regimen including cisplatin was administered to a man with extragonadal seminoma and cisplatin-induced acute renal failure. Three doses of cisplatin (30, 50, and 100 mg/m2) were given in conjunction with hemodialysis. Pharmacokinetic data for free and total plasma platinum were obtained. The patient also received one dose of carboplatin and a course of radiation therapy. Complete remission was achieved, and useful renal function returned. Cisplatin can be used successfully during acute renal failure.
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