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MR-guided balloon angioplasty of stenosed aorta: In vivo evaluation using near-standard instruments and a passive tracking technique

2000; Wiley; Volume: 12; Issue: 4 Linguagem: Inglês

10.1002/1522-2586(200010)12

1522-2586

Fran�ois Godart, Jean-Paul Bérégi, Lionel Nicol, B Occelli, André Vincentelli, Vincent Daanen, Christian Rey, Jean Rousseau,

Cardiac Imaging and Diagnostics

The purpose of this study was to assess the feasibility of magnetic resonance (MR)-guided balloon angioplasty of a stenosed aorta on an open low-field magnet using a passive tracking technique. Visualization of vessels and position of instruments were realized by using a fast low-angle shot (FLASH) sequence. Catheters and guidewire were prepared for susceptibility-based MR visualization. Standard balloon catheters were inflated with diluted gadolinium, and nitinol guidewires were modified by incorporation of iron oxide markers into their walls. After validation on a flow phantom, balloon angioplasty was performed on an in vivo model of arterial stenosis. Creation of abdominal aorta stenosis was realized in five piglets. MR-guided balloon angioplasty of the aorta was performed with success in all but one. In one of them, stent implantation was achieved in the descending aorta. Balloon angioplasty using a passive tracking technique is a simple concept that can be realized with near-standard instruments and any MR imaging system. This represents an advance toward MR-guided vascular interventions in the future.