Produção Nacional
Revisado por pares
Potassium iodide capsule treatment of feline sporotrichosis
2012; SAGE Publishing; Volume: 14; Issue: 6 Linguagem: Inglês
10.1177/1098612x12441317
ISSN1532-2750
AutoresÉrica Guerino dos Reis, Isabella Dib Ferreira Gremião, A. Kitada, Raphael Francisco Dutra Barbosa da Rocha, Verônica Souza Paiva Castro, Mônica B. L. Barros, Rodrigo Caldas Menezes, Sandro Antônio Pereira, T. M. P. Schubach,
Tópico(s)Parasitic Infections and Diagnostics
ResumoSporotrichosis is a mycosis caused by Sporothrix schenckii. The most affected animal is the cat; it has played an important role in the zoonotic transmission of this disease, especially in Rio de Janeiro, Brazil, since 1998. In order to evaluate the treatment of feline sporotrichosis with potassium iodide, an observational cohort was conducted in 48 cats with sporotrichosis at Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz. All cats received potassium iodide capsules, 2.5 mg/kg to 20 mg/kg q24h. The cure rate was 47.9%, treatment failure was 37.5%, treatment abandonment was 10.4% and death was 4.2%. Clinical adverse effects were observed in 52.1% of the cases. Thirteen cats had a mild increase in hepatic transaminase levels during the treatment, six of them presented clinical signs suggestive of hepatotoxicity. Compared to previous studies with itraconazole and iodide in saturated solution, potassium iodide capsules are an alternative for feline sporotrichosis treatment.
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