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Evolutionary history of 7SL RNA-derived SINEs in Supraprimates

2007; Elsevier BV; Volume: 23; Issue: 4 Linguagem: Inglês

10.1016/j.tig.2007.02.002

1362-4555

Jan Ole Kriegs, Gennady Churakov, Jerzy Jurka, Jürgen Brosius, Jürgen Schmitz,

Genomics and Phylogenetic Studies

The evolutionary relationships of 7SL RNA-derived SINEs such as the primate Alu or the rodent B1 elements have hitherto been obscure. We established an unambiguous phylogenetic tree for Supraprimates, and derived intraordinal relationships of the 7SL RNA-derived SINEs. As well as new elements in Tupaia and primates, we also found that the purported ancestral fossil Alu monomer was restricted to Primates, and provide here the first description of a potential chimeric promoter box region in SINEs. The evolutionary relationships of 7SL RNA-derived SINEs such as the primate Alu or the rodent B1 elements have hitherto been obscure. We established an unambiguous phylogenetic tree for Supraprimates, and derived intraordinal relationships of the 7SL RNA-derived SINEs. As well as new elements in Tupaia and primates, we also found that the purported ancestral fossil Alu monomer was restricted to Primates, and provide here the first description of a potential chimeric promoter box region in SINEs.