Towards Recyclable NAD(P)H Regeneration Catalysts
2012; Multidisciplinary Digital Publishing Institute; Volume: 17; Issue: 8 Linguagem: Inglês
10.3390/molecules17089835
ISSN1433-1373
AutoresMiriam de Torres, Jonas Dimroth, Isabel W. C. E. Arends, Juliane Keilitz, Frank Hollmann,
Tópico(s)Nanomaterials for catalytic reactions
ResumoRh(III)-TsDPEN, an immobilized analog of the well-known [Cp*Rh(bpy)(H2O)]2+ was evaluated as a heterogeneous, recyclable regeneration catalyst for reduced oxidoreductase cofactors [NAD(P)H]. Repeated use of this catalyst was established and the catalytic properties were initially investigated. Apparently, Rh(III)-TsDPEN is prone to severe diffusion limitations, necessitating further developments. Overall, a promising concept for chemoenzymatic redox catalysis is proposed, which may overcome some of the current limitations such as catalyst cost and incompatibility of Rh with some biocatalysts.
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