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Increased erythrocyte 2,3-DPG: Usefulness during hypoxia

1974; Elsevier BV; Volume: 16; Issue: 6 Linguagem: Inglês

10.1016/0022-4804(74)90087-0

1095-8673

H. J. PROCTOR, James Fry,

Heme Oxygenase-1 and Carbon Monoxide

Abstract Ten hypoxic patients were randomly treated with either intravenous saline or intravenous inosine, pyruvate, and inorganic phosphate (IPP). IPP proved to be an easy, nontoxic method of rapidly increasing erythrocyte 2,3-DPG. There was no evidence of improved tissue oxygenation in association with increased concentrations or erythrocyte 2,3-DPG. Several alternative interpretations of the data are presented.