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First stereoselective synthesis of D-amino acid N-alkyl amide catalyzed by D-aminopeptidase

1989; Elsevier BV; Volume: 45; Issue: 18 Linguagem: Inglês

10.1016/s0040-4020(01)89103-1

1464-5416

Yasuo Kato, Yasuhisa Asano, Akiko Nakazawa, Kiyosi Kondô,

Glycosylation and Glycoproteins Research

The first stereoselective synthesis of D-amino acid N-alkyl amides was achieved by the use of D-aminopeptidase from Ochrobactrum anthropi. The enzyme immobilized by urethane prepolymer PU-6 catalyzed aminolysis reaction of racemic amino acid esters in organic solvents.