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Can living in the surroundings of a petrochemical complex be a risk factor for autoimmune thyroid disease?

2009; Elsevier BV; Volume: 110; Issue: 1 Linguagem: Inglês

10.1016/j.envres.2009.10.009

1096-0953

Clarice Umbelino de Freitas, Rosária A. Grimaldi Campos, Mirta Alcira F. Rodrigues Silva, Maria Rosana Issberner Panachão, José Cássio de Moraes, William Waissmann, Antônio Roberto Chacra, Marina Y. S. Maeda, Regina Sorrentino Minazzi Rodrigues, James Gonçalves Belchor, Sonia Oliveira Barbosa, R. T. M. Santos,

Salivary Gland Disorders and Functions

Based on a suspicion raised by a health professional and due to a subsequent legal request, a cross-sectional study was made with a comparison group to investigate a possible excess of Hashimoto's thyroiditis-HT and antibodies-ATA in the surroundings of a Petrochemical Complex.People of both sexes aged over 20 years were investigated in a random sample of residents in the area surrounding the Petrochemical Complex. Controls were investigated in an area with steel industries. In the areas searched, participants were chosen randomly and stratified a priori by sex and age group. As a result, 90.5% of the expected sample was obtained, totaling 1533 individuals. HT and ATA prevalences were compared by the chi-square test. Logistic regression was used to control the possible confounding factors for HT and ATA.Both TH (9.3%) and ATA (17.6%) prevalences were higher in the Petrochemical Complex area than in the control area (3.9% and 10.3%, respectively). After controlling the possible confounding factors, the POR for living in the surroundings of the Complex and presenting HT was 2.39 (CI95%: 1.42-4.03). According to the ATA criterion, the POR for living in the surroundings of the Complex was 1.78 (CI95%: 1.23-2.60).The authors have found higher prevalence and risk of developing thyroiditis and anti-thyroid antibodies among residents of areas surrounding the Petrochemical Complex and think these findings need to be further studied in similar areas.