Prostglandin E in the secretions of allergic rhinitis
1977; Elsevier BV; Volume: 13; Issue: 4 Linguagem: Inglês
10.1016/0090-6980(77)90239-8
ISSN1878-416X
AutoresTadao Okazaki, Robert E. Reisman, Carl E. Arbesman,
Tópico(s)Antimicrobial Peptides and Activities
ResumoProstaglandin (PG) was extracted from nasal secretions of individuals with hay fever and from nasal washings of normal subjects. The extract was chromatographed in a silicic acid column and the purified PGE fraction was converted to PGB by alkaline dehydration. The PGB was then measured by a competitive radioimmunoassay with tritiated PGB1 and anti-PGB1 antibody, employing the double antibody technique. PGE was detected in the secretions of 6 of 12 hay fever patients and in the pooled normal nasal washings.
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