CD34 + AC133 + Cells Isolated from Cord Blood are Highly Enriched in Long‐Term Culture‐Initiating Cells, NOD/SCID‐Repopulating Cells and Dendritic Cell Progenitors
1998; Oxford University Press; Volume: 16; Issue: 6 Linguagem: Inglês
10.1002/stem.160387
ISSN1549-4918
AutoresErika A. de Wynter, David Buck, Claire A. Hart, R. Heywood, L. H. Coutinho, Aled Clayton, Joseph A. Rafferty, Deborah J. Burt, Guillermo Güenechea, Juan A. Bueren, D. Gagen, LJ Fairbairn, B. I. Lord, Nydia G. Testa,
Tópico(s)T-cell and B-cell Immunology
ResumoThe AC133 antigen is a novel antigen selectively expressed on a subset of CD34+ cells in human fetal liver, bone marrow, and blood as demonstrated by flow cytometric analyses. In this study, we have further assessed the expression of AC133 on CD34+ cells in hemopoietic samples and found that there was a highly significant difference between normal bone marrow and cord blood versus aphereses (p <0.0001) but not between bone marrow and cord blood.
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