Sequence of a newly identified Mycobacterium tuberculosis gene encoding a protein with sequence homology to virulence-regulating proteins
1993; Elsevier BV; Volume: 126; Issue: 1 Linguagem: Inglês
10.1016/0378-1119(93)90607-5
ISSN1879-0038
AutoresSeema Gupta, Akhilesh K. Tyagi,
Tópico(s)Biochemical and Molecular Research
ResumoAnalysis of the nucleotide sequence of a gene cloned from a Mycobacterium tuberculosis H37Rv genomic library predicted a 339-amino-acid protein with an Mr of 37656. The protein exhibited significant homology with the Cfad, FapR and Rns proteins from different enterotoxigenic strains of Escherichia coli, VirF protein of Shigella and VirFy protein of Yersinia, all of which regulate virulence-associated genes.
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