Synthesis and PDF inhibitory activities of novel benzothiazolylidenehydroxamic acid derivatives
2003; Elsevier BV; Volume: 13; Issue: 19 Linguagem: Inglês
10.1016/s0960-894x(03)00675-9
ISSN1464-3405
AutoresWataru Takayama, Yoshihisa Shirasaki, Y. Sakai, Emi Nakajima, Shuhei Fujita, Kanako Sakamoto-Mizutani, Jun Inoue,
Tópico(s)Peptidase Inhibition and Analysis
ResumoA novel series of benzothiazolylidenehydroxamic acid derivatives has been designed and synthesized as PDF inhibitors. Some of this novel class of PDF inhibitors exhibited micromolar order enzyme inhibitory activity and antibacterial activity.
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