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2-Deceno- δ -lactone-producing Fungi, Strains of Fusarium solani , Isolated by Using a Medium Containing Decano- δ -lactone as the Sole Carbon Source

1993; Oxford University Press; Volume: 57; Issue: 12 Linguagem: Inglês

10.1271/bbb.57.2107

1347-6947

Hiroshi Nago, Miwako Matsumoto, Shuryo Nakai,

Microbial Natural Products and Biosynthesis

A screening procedure for microorganisms which have an ability to produce a desired compound as their secondary metabolite is first proposed. In some cases, the target microorganisms can be expected to grow and be enriched in a medium containing the desired compound, namely one of the secondary metabolites of the microorganisms, as the sole source of carbon, degrading and assimilating the compound to the primary metabolites. This approach was applied to isolate alkano-δ-lactones producing fungi by using a medium containing alkano-δ-lactones as the sole source of carbon. We isolated Fusarium solani and Trichoderma viride that had the ability to biosynthesize 2-deceno-δ-lactone (massoialactone) and 2,4-decadieno-δ-lactone(6-pentyl-δ-pyrone), respectively, in a glucose medium.