A short and efficient stereoselective synthesis of dihydrosphingosine triacetate
1999; Elsevier BV; Volume: 10; Issue: 24 Linguagem: Inglês
10.1016/s0957-4166(99)00578-9
ISSN1362-511X
AutoresRodney A. Fernandes, Pradeep Kumar,
Tópico(s)Marine Sponges and Natural Products
ResumoA highly enantiocontrolled synthesis of d-(+)-erythro-dihydrosphingosine (sphinganine) triacetate is described using the Sharpless asymmetric dihydroxylation and the regiospecific nucleophilic opening of a cyclic sulfite as key steps.
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