Artigo Acesso aberto Revisado por pares

Irish cardiac society

1993; Springer Science+Business Media; Volume: 162; Issue: 5 Linguagem: Inglês

10.1007/bf02945184

ISSN

1863-4362

Autores

Christopher Cullen, Gilbert MacKenzie, J. Adgey, F. Lavin, M. Keane, A. M. Forde, Pratik Shah, Frank Gannon, Kieran Daly, Brian M. McClements, Amanda McNeil, C. M. Wilson, Sharon Webb, N. P. S. Campbell, Mazhar M. Khan, Brian O’Murchu, Bernard J. Gersh, Kent R. Bailey, David R. Holmes, Daniel Foley, Walter Hermans, Benno J. Rensing, J. Cornelis de Vos, J-P Herman, Patrick Serruys, Anne F. Mannion, Joshua Finn, H. Grimes, M. Lonergan, O’Donnell, L. Daly, E. McGovern, Ian Graham, P.A. Joseph, K. Robinson, Thomas Kinsella, P. Crean, G. Gearty, Mike Walsh, Marie Ryan, Robert Clarke, R. Refsum, Per Magne Ueland, D. J. Coehrane, A. J. Stewart, David McEneaney, J. D. Allen, Jack Anderson, G. Dempsey, A.A.J. Adgey, F. Casey, Helen Mulholland, B. Craig, R.M.H. Power, N. Rooney, D. B. O’Keeffe, Janet M. McComb, C. M. Wilson, Kim Song Tan, Clifton Pye, Natalie McCabe, N Hickey, David McEneaney, D. Cochrane, Paul Oslizlok, C. L. Case, P C Gillette, Barbara J. Knick, Leigh Henry, Larisa Blair, T. Gumbrielle, John Bourke, Colin J. Hilton, R. Wayne Campbell, Patricia Kearney, Francis Fennell, Susan McKiernan, William H. Fennell, Javier Escaned, Walter Hermans, Victor A. Umans, Peter P. de Jaegere, Pim J. de Feyter, J. Galvin, Sean F. Leavey, D. Sugrue, StephenR. Vallely, N. P. S. Campbell, John Laird, R. Ferguson, S. Duff, A. B. Bridges, T. H. Pringle, G P McNeill, M. McLaren, J. J. F. Belch, Lydia O’Sullivan, H. Foster Bain, Stephen K. Hunter, Christopher Wren, A. Hennesy, Mary Codd, C. Daly, Cormac McCarthy, K. Carroll, Fergus V. Coakley, Siobhain M. O’Mahony, P. A. Sullivan, Patricia Kearney, Tom Higgins, J. J Crowey, Seamas C. Donnelly, Moira Tobin, Oliver FitzGerald, Barry Bresnihan, B. Maurer, P. J. Quigley, Emer Shelley, C. Collins, N Hickey, Ristexrd V uLCAHY, P. W. Johnston, Jonathan Gibson, Philip Crowe, G. R. Gnana King, P. Freyne, Grayson G. Geary, Brendan McAdam, Richard G. Sheahan, Nadia El Gaylani, Amber L. Simpson, I. Temperley, F Mulcahy, Hannah McGee, T W GRAHAM, Brooks R. Crowe, John Horgan, J. McGinley, J. Hurley, M. Neligan, Charles Austin, John G.F. Cleland, D Gladstone, Hugh O’Kane, John O’Sullivan, Ali Hasan, J.R.L. Hamilton, Stephen K. Hunter, John H. Dark, C. M. McDaid, Anne S. Phillips, S. A. Lewis, T. J. McMurray, Kevin Walsh, S. E. Abrams, Michael J. Diamond, M.J. Clarkson, Wolfgang Rutsch, Håkan Emanuelsson, Nicolas Danchin, William Wijns, François Chappuis,

Tópico(s)

Research in Social Sciences

Resumo

Three dimensional body surface maps provide more information on the gee-spatial distribution of cardiac elactrieal activity.It is hypo thesised that this information could facilitate the diagnosis of acute MI in early cases where standard methods are equivocal.To date these techniques have been confined to the laboratory and have yet to find clinical application.An important first step is the assessment of their diagnostic value among patients with established MI.All 82 consecutive patients admitted to the RVH cardiac unit with first presentation ofchastpaln suggestive of MI were mapped at 24 hours using a Corazonix BSM-32 predieter which measured QRS and STT iso-lntegrals using 32 leads.Of the 82 patients, 57 (69.5%) had an initial diagnostic ECG with subsequent confirmatory enzyme elevation.A further 25 (30.5%)presented with nondiagnostic ECG f'mdings.Fifteen of this group had an MI as confirmed by an increase in cardiac enzymes.For comparative purposes, 54 consols were recruited and mapped, all with normal ECG and no IHD risk factors.A series of discriminant function analyses were performed to assess sensitivity and specificity.Using a subset of the 32 QRS and the 32 STT iso-integralmeasurements, selected by a stepwise forward algorithm, a sensitivity of 94.7% (54/57) and a specificity of 90.7% (49/54) was obtained.When all measurements were analysed together, better results were obtained: sensitivity 10070 (57]57) and specificity 96.3 (42/ 54).In further multivariate analysis, map topography differed significantly (p<< 0.01) between males and females.Separating the data according to sex and using all QRS and sTr iso-integral measurements, 100% specificity and sensitivity resulted.Despite these findings, each of the derived discriminam functions had difficulty in classifying the 25 cases belonging to the possible MI group.The best results obtainable were: a sensitivity of 60% and a specificity of 60%.This suggests that further analysis is required to identify the topography of these patients.

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